Research workbench
Structure of btdm-bound human TRPC6 nanodisc at 2.9 ångström in high calcium state
Analyse Structure of btdm-bound human TRPC6 nanodisc at 2.9 ångström in high calcium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DXF
- Type
- protein
- Length
- 2,740 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y210
- Ligands
- Y01, W99, POV, 98R, CA, ZN
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 685 | — | Q9Y210 |
Ligands and binding sites
- Y01 · Cholesterol hemisuccinate · ligand · 12 copies · chains A, B, C, D
- W99 · [2-(1,3-benzodioxol-5-ylamino)-1,3-thiazol-4-yl]-[(3R, 5S)-3,5-dimethylpiperidin-1-yl]methanone · ligand · 4 copies · chains A, D, B, C
- POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · ligand · 4 copies · chains A, B, D, C
- 98R · [(2S)-2-[(E)-octadec-10-enoyl]oxy-3-oxidanyl-propyl] octadec-10-enoate · ligand · 4 copies · chains A, D, B, C
- CA · Calcium ion · metal · 12 copies · chains A, B, C, D
- ZN · Zinc ion · metal · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7DXF · Structure of BTDM-bound human TRPC6 nanodisc at 2.9 angstrom in high calcium state · the same entry in another collection · chain A against A, TM-score 1.00
- Q9Y210 · AlphaFold monomer V2.0 prediction for short transient receptor potential channel 6… · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y210
- Elsewhere: RCSB PDB 7DXF · PDBe 7DXF · UniProt Q9Y210
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