Research workbench
Voltage-gated sodium channel NAV1.1 and BETA4
Analyse Voltage-gated sodium channel NAV1.1 and BETA4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DTD
- Type
- protein
- Length
- 1,249 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8IWT1, P35498
- Ligands
- 9Z9, NAG
Structure
electron microscopy · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 111 | — | Q8IWT1 |
| A | — | protein | 1138 | — | P35498 |
Ligands and binding sites
- 9Z9 · (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7DTD · Voltage-gated sodium channel Nav1.1 and beta4 · the same entry in another collection · chain A against A, TM-score 1.00
- P35498 · AlphaFold monomer V2.0 prediction for sodium channel protein type 1 subunit alpha (P35498) · a predicted model of the same protein · chain A against A, TM-score 0.98
- Q8IWT1 · AlphaFold monomer V2.0 prediction for sodium channel subunit beta-4 (Q8IWT1) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IWT1
- Every structure of UniProt P35498
- Elsewhere: RCSB PDB 7DTD · PDBe 7DTD · UniProt Q8IWT1 · UniProt P35498
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