UniProt Q8IWT1
Sodium channel subunit beta-4 (Q8IWT1)
Sodium channel subunit beta-4 (UniProt Q8IWT1): 10 experimental structures and 1 predicted model on GenesisL1. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IWT1
- Protein
- Sodium channel subunit beta-4
- Experimental structures
- 10
- Predicted models
- 1
Structures
11 records of Q8IWT1 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4MZ2 | Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain | x-ray diffraction | A | — | — |
| 4MZ2 | Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain | x-ray diffraction | A | — | — |
| 4MZ3 | Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W… | x-ray diffraction | A, B | — | — |
| 4MZ3 | Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W… | x-ray diffraction | A, B | — | — |
| 5XAW | Parallel homodimer structures of voltage-gated sodium channel beta4 for cell-cell adhesion | x-ray diffraction | A, B | — | — |
| 5XAW | Parallel homodimer structures of voltage-gated sodium channel BETA4 for cell-cell adhesion | x-ray diffraction | A, B | — | — |
| 6VSV | Crystal structure of a disease mutant of the Voltage-gated Sodium Channel Beta 4 subunit… | x-ray diffraction | A | — | — |
| 6VSV | Crystal structure of a disease mutant of the voltage-gated sodium channel beta 4 subunit… | x-ray diffraction | A | — | — |
| 7DTD | Voltage-gated sodium channel Nav1.1 and beta4 | electron microscopy | B | — | — |
| 7DTD | Voltage-gated sodium channel NAV1.1 and BETA4 | electron microscopy | B | — | — |
| Q8IWT1 | AlphaFold monomer V2.0 prediction for sodium channel subunit beta-4 (Q8IWT1) | predicted | A | — | — |
Experiment against prediction
- 7DTD chain B against the predicted model Q8IWT1: TM-score 0.95, RMSD 0.91 Å
- 7DTD chain B against the predicted model Q8IWT1: TM-score 0.95, RMSD 0.91 Å
- 4MZ2 chain A against the predicted model Q8IWT1: TM-score 0.95, RMSD 0.92 Å
- 4MZ2 chain A against the predicted model Q8IWT1: TM-score 0.95, RMSD 0.92 Å
- 6VSV chain A against the predicted model Q8IWT1: TM-score 0.92, RMSD 1.52 Å
- 6VSV chain A against the predicted model Q8IWT1: TM-score 0.92, RMSD 1.52 Å
- 5XAW chain A against the predicted model Q8IWT1: TM-score 0.91, RMSD 1.65 Å
- 5XAW chain A against the predicted model Q8IWT1: TM-score 0.91, RMSD 1.65 Å
- 5XAW chain B against the predicted model Q8IWT1: TM-score 0.90, RMSD 1.67 Å
- 5XAW chain B against the predicted model Q8IWT1: TM-score 0.90, RMSD 1.67 Å
Elsewhere
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