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PI3KC2ADELTAN and deltac-C2

Analyse PI3KC2ADELTAN and deltac-C2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7BI2
Type
protein
Length
1,021 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
Q61194
Ligands
17G, IOD

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein1021—Q61194

Ligands and binding sites

  • 17G · 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl) phenyl]benzo[h][1,6]naphthyridin-2(1H)-one · ligand · chains A
  • IOD · Iodide ion · ion · 5 copies · chains A
  • EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7BI2 · PI3KC2aDeltaN and DeltaC-C2 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q61194 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-phosphate 3-kinase C2… · a predicted model of the same protein · chain A against A, TM-score 0.83

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