UniProt Q61194
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (Q61194)
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha,Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (UniProt Q61194), EC 2.7.1.137, 2.7.1.153: 14 experimental structures on…
- UniProt
- Q61194
- Protein
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit…
- EC
- 2.7.1.137, 2.7.1.153, 2.7.1.154
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 32 · 3 records with a druggable one
Structures
14 records of Q61194 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B3R | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2 | x-ray diffraction | A, B | — | — |
| 2B3R | Crystal structure of the C2 domain of class II phosphatidylinositide 3-kinase C2 | x-ray diffraction | A, B | — | — |
| 7BI2 | PI3KC2aDeltaN and DeltaC-C2 | x-ray diffraction | A | 17G, IOD | 12 (best 0.84) |
| 7BI2 | PI3KC2ADELTAN and deltac-C2 | x-ray diffraction | A | 17G, IOD | — |
| 7BI4 | PI3KC2a core apo | x-ray diffraction | A | SO4 | 13 (best 0.85) |
| 7BI4 | PI3KC2A core apo | x-ray diffraction | A | SO4 | — |
| 7BI6 | PI3KC2A core in complex with ATP | x-ray diffraction | A | ATP, SO4, MG | — |
| 7BI9 | PI3KC2A core in complex with PIK90 | x-ray diffraction | A | 090 | — |
| 7Z74 | PI3KC2A core in complex with PITCOIN2 | x-ray diffraction | A | IKC | — |
| 7Z75 | PI3KC2a core in complex with PITCOIN3 | x-ray diffraction | A | IG3, SO4 | 7 (best 0.84) |
| 7Z75 | PI3KC2A core in complex with PITCOIN3 | x-ray diffraction | A | IG3, SO4 | — |
| 8A9I | PI3KC2a core in complex with PITCOIN1 | x-ray diffraction | A | TSW, SO4 | — |
| 8A9I | PI3KC2A core in complex with PITCOIN1 | x-ray diffraction | A | TSW, SO4 | — |
| Q61194 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-phosphate 3-kinase C2… | — | — | — |
Ligands
- SO4 · Sulfate ion · in 7 records
- 17G · 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl) phenyl]benzo[h][1,6]naphthyridin-2(1H)-one · in 2 records
- IG3 · ~{N}-[4-[3-(methylsulfonylamino)phenyl]-1,3-thiazol-2-yl]-2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-ethanamide · in 2 records
- IOD · Iodide ion · in 2 records
- TSW · 2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-~{N}-(1,3-thiazol-2-yl)ethanamide · in 2 records
- 090 · N-(2,3-dihydro-7,8-dimethoxyimidazo[1,2-C] quinazolin-5-yl)nicotinamide · in 1 record
- ATP · Adenosine-5'-triphosphate · in 1 record
- IKC · ~{N}-[4-(3-hydroxyphenyl)-1,3-thiazol-2-yl]-2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-ethanamide · in 1 record
- MG · Magnesium ion · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.