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Ligand · IKC

IKC · ~{N}-[4-(3-hydroxyphenyl)-1,3-thiazol-2-yl]-2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-ethanamide

IKC, ~{N}-[4-(3-hydroxyphenyl)-1,3-thiazol-2-yl]-2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-ethanamide (C25 H20 N6 O3 S2, 516.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…

Component
IKC
Formula
C25 H20 N6 O3 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

IKC in 2 structures; the first of them:

  • 7Z74 · PI3KC2a core in complex with PITCOIN2 · IKC A1101 · binds PHE730, SER731, SER732, LYS738, ASN752, MET754, PHE790, VAL802 and 9 more
  • 7Z74 · PI3KC2A core in complex with PITCOIN2 · IKC A1101 · binds PHE730, SER731, SER732, LYS738, ASN752, MET754, PHE790, VAL802 and 8 more

Residues it binds most

SER 2, PHE 2, MET 2, VAL 2, ALA 2, ASN 2, GLU 2, ILE 2, LEU 2, LYS 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol

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