Pseudomonas stutzeri nitrous oxide reductase mutant, H382A

Structure

x-ray diffraction · 2 distinct chains · 11% helix, 41% strand (DSSP).

Ligands and binding sites

• CUA · Dinuclear copper ion · ligand · 2 copies · chains A, B
• K7E · sulfanyl-(tricuprio-$l^{4}-sulfanyl)copper · ligand · chains A, B
• PHE · Phenylalanine · ligand · chains B
• RUQ · (dicuprio-$l^{3}-sulfanyl)-sulfanyl-copper · ligand · chains A, B
• CA · Calcium ion · metal · 2 copies · chains A, B
• K · Potassium ion · metal · 2 copies · chains A, B
• NA · Sodium ion · metal · chains A
• CL · Chloride ion · ion · 3 copies · chains A, B
• B3P · 2-[3-(2-hydroxy-1,1-dihydroxymethyl-ethylamino)-propylamino]-2-hydroxymethyl-propane-1,3-diol · additive · 2 copies · chains A, B
• FMT · Formic acid · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Interfaces

1 interface between chains.

• A–B · 5897 Ų buried · 73 hydrogen bonds · protein-protein

Compared structures

• 7AQA · Pseudomonas stutzeri nitrous oxide reductase mutant, H382A · the same entry in another collection · chain A against A, TM-score 1.00
• P19573 · AlphaFold monomer V2.0 prediction for nitrous-oxide reductase (P19573) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P19573
• Elsewhere: RCSB PDB 7AQA · PDBe 7AQA · UniProt P19573