Research workbench
Repulsive guidance molecule C (rgmc, hemojuvelin, hjv, HFE2) in complex with growth differentiation factor 5 (GDF5)
Analyse Repulsive guidance molecule C (rgmc, hemojuvelin, hjv, HFE2) in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6Z3L
- Type
- protein
- Length
- 157 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GROWTH/DIFFERENTIATION factor 5; Hemojuvelin
- UniProt
- P43026, Q6ZVN8
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | GROWTH/DIFFERENTIATION factor 5 | protein | 105 | 18% helix, 45% strand | P43026 |
| B | Hemojuvelin | protein | 52 | 60% helix, 0% strand | Q6ZVN8 |
Interfaces
1 interface between chains.
- A–B · 411 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 6Z3L · Repulsive Guidance Molecule C (RGMC, Hemojuvelin, HJV, HFE2) in complex with Growth… · the same entry in another collection · chain A against A, TM-score 1.00
- P43026 · AlphaFold monomer V2.0 prediction for GROWTH/DIFFERENTIATION factor 5 (P43026) · a predicted model of the same protein · chain A against A, TM-score 0.93
- Q6ZVN8 · AlphaFold monomer V2.0 prediction for hemojuvelin (Q6ZVN8) · a predicted model of the same protein · chain B against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P43026
- Every structure of UniProt Q6ZVN8
- Elsewhere: RCSB PDB 6Z3L · PDBe 6Z3L · UniProt P43026 · UniProt Q6ZVN8
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