UniProt Q6ZVN8
Hemojuvelin (Q6ZVN8)
Hemojuvelin (UniProt Q6ZVN8): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6ZVN8
- Protein
- Hemojuvelin
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 2 records with a druggable one
Structures
5 records of Q6ZVN8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UI1 | Crystal structure of the human RGMC-BMP2 complex | x-ray diffraction | C, D | CL, NO3 | 6 (best 0.59) |
| 4UI1 | Crystal structure of the human rgmc-BMP2 complex | x-ray diffraction | C, D | CL, NO3 | 6 (best 0.59) |
| 6Z3L | Repulsive Guidance Molecule C (RGMC, Hemojuvelin, HJV, HFE2) in complex with Growth Differentiation… | x-ray diffraction | B | — | — |
| 6Z3L | Repulsive guidance molecule C (rgmc, hemojuvelin, hjv, HFE2) in complex with growth differentiation… | x-ray diffraction | B | — | — |
| Q6ZVN8 | AlphaFold monomer V2.0 prediction for hemojuvelin (Q6ZVN8) | predicted | A | — | 3 (best 0.50) |
Ligands
Experiment against prediction
- 4UI1 chain C against the predicted model Q6ZVN8: TM-score 0.93, RMSD 1.18 Å
- 4UI1 chain C against the predicted model Q6ZVN8: TM-score 0.93, RMSD 1.18 Å
- 4UI1 chain D against the predicted model Q6ZVN8: TM-score 0.90, RMSD 0.82 Å
- 4UI1 chain D against the predicted model Q6ZVN8: TM-score 0.90, RMSD 0.82 Å
- 6Z3L chain B against the predicted model Q6ZVN8: TM-score 0.89, RMSD 0.90 Å
- 6Z3L chain B against the predicted model Q6ZVN8: TM-score 0.89, RMSD 0.90 Å
Elsewhere
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