Crystal structure of an antiparallel octameric transmembrane coiled coil K2-cctm-vbic

Structure

x-ray diffraction · 1 distinct chain · 94% helix, 0% strand (DSSP).

Ligands and binding sites

• ACE · Acetyl group · ligand · 4 copies · chains A, B, C, D
• GLY · Glycine · ligand · 2 copies · chains B, C
• NH2 · Amino group · ion · 4 copies · chains A, B, C, D
• 2PE · Nonaethylene glycol · additive · 2 copies · chains B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

6 interfaces between chains.

• C–D · 687 Ų buried · 1 hydrogen bond · protein-protein
• A–B · 686 Ų buried · 1 hydrogen bond · protein-protein
• B–C · 605 Ų buried · 29 hydrogen bonds · protein-protein
• A–D · 583 Ų buried · 34 hydrogen bonds · protein-protein
• A–C · 86 Ų buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 covalent (covalent ligand).

Compared structures

• 6YB1 · Crystal structure of an antiparallel octameric transmembrane coiled coil K2-CCTM-VbIc · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Elsewhere: RCSB PDB 6YB1 · PDBe 6YB1