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Human cyclophilin D in complex with 2-(exo-3,5-dioxo-4-aza- TRICYCLO[5.2.1.02,6]DEC-4-yl)-N-((1R,9R,10S)-10-hydroxy-12-oxa-8-aza- TRICYCLO[7.3.1.02,7]TRIDECA-2(7),3,5-trien-4-ylmethyl)-acetamide

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PDB: 6R8W
Type: protein
Length: 164 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peptidyl-prolyl cis-trans isomerase F, mitochondrial
EC: 5.2.1.8
UniProt: P30405
Ligands: O4B, JVH

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Peptidyl-prolyl cis-trans isomerase F, mitochondrial (EC 5.2.1.8)	protein	164	15% helix, 34% strand	P30405

Ligands and binding sites

O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane · ligand · chains A
JVH · 2-(exo-3,5-Dioxo-4-aza-tricyclo[5.2.1.02,6]dec-4-yl)-N-((1R,9R,10S)-10-hydroxy-12-oxa-8-aza-tricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ylmethyl)-acetamide · ligand · chains A
P6G · Hexaethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6R8W · Human Cyclophilin D in complex with 2-(exo-3,5-Dioxo-4-aza-tricyclo[5.2.1.02,6]dec-4-yl)-N… · the same entry in another collection · chain A against A, TM-score 1.00

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Every structure of UniProt P30405
Elsewhere: RCSB PDB 6R8W · PDBe 6R8W · UniProt P30405

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