UniProt P30405
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (P30405)
Peptidyl-prolyl cis-trans isomerase F, mitochondrial (UniProt P30405), EC 5.2.1.8: 116 experimental structures on GenesisL1, 31 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P30405
- Protein
- Peptidyl-prolyl cis-trans isomerase F, mitochondrial
- EC
- 5.2.1.8
- Experimental structures
- 116
- Predicted models
- 0
- Ligands
- 31
- Pockets
- 16 · 2 records with a druggable one
Structures
116 records of P30405 in the MolNFT archive: 116 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2BIT | Crystal structure of human cyclophilin D at 1.7 A resolution | x-ray diffraction | X | — | — |
| 2BIT | Crystal structure of human cyclophilin D at 1.7 a resolution | x-ray diffraction | X | — | — |
| 2BIU | Crystal structure of human cyclophilin D at 1.7 A resolution, DMSO complex | x-ray diffraction | X | — | — |
| 2BIU | Crystal structure of human cyclophilin D at 1.7 a resolution, dmso complex | x-ray diffraction | X | — | — |
| 2Z6W | Crystal structure of human cyclophilin D in complex with cyclosporin A | x-ray diffraction | A, B | — | — |
| 2Z6W | Crystal structure of human cyclophilin D in complex with cyclosporin a | x-ray diffraction | A, B | — | — |
| 3QYU | Crystal structure of human cyclophilin D at 1.54 A resolution at room temperature | x-ray diffraction | A | — | — |
| 3QYU | Crystal structure of human cyclophilin D at 1.54 a resolution at room temperature | x-ray diffraction | A | — | — |
| 3R49 | Human cyclophilin D complexed with quinolin-8-amine | x-ray diffraction | A | — | — |
| 3R49 | Human cyclophilin D complexed with quinolin-8-amine | x-ray diffraction | A | — | — |
| 3R4G | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3R4G | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3R54 | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3R54 | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3R56 | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3R56 | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3R57 | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3R57 | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3R59 | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3R59 | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3RCF | Human cyclophilin D complexed with N-[(4-aminophenyl)sulfonyl]benzamide | x-ray diffraction | A | — | — |
| 3RCF | Human cyclophilin D complexed with N-[(4-aminophenyl) SULFONYL]BENZAMIDE | x-ray diffraction | A | — | — |
| 3RCG | Human cyclophilin D complexed with dimethylformamide | x-ray diffraction | A | — | — |
| 3RCG | Human cyclophilin D complexed with dimethylformamide | x-ray diffraction | A | — | — |
| 3RCI | Human cyclophilin D complexed with 5-methyl-1,2-oxazol-3-amine | x-ray diffraction | X | — | — |
| 3RCI | Human cyclophilin D complexed with 5-methyl-1,2-oxazol-3-amine | x-ray diffraction | X | — | — |
| 3RCK | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | X | — | — |
| 3RCK | Human cyclophilin D complexed with a fragment | x-ray diffraction | X | — | — |
| 3RCL | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3RCL | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3RD9 | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | X | — | — |
| 3RD9 | Human cyclophilin D complexed with a fragment | x-ray diffraction | X | — | — |
| 3RDA | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | X | — | — |
| 3RDA | Human cyclophilin D complexed with a fragment | x-ray diffraction | X | — | — |
| 3RDB | Human Cyclophilin D Complexed with a Fragment | x-ray diffraction | A | — | — |
| 3RDB | Human cyclophilin D complexed with a fragment | x-ray diffraction | A | — | — |
| 3RDC | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | A | — | — |
| 3RDC | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | A | — | — |
| 4J58 | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | A | — | — |
| 4J58 | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | A | — | — |
| 4J59 | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | A | — | — |
| 4J59 | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | A | — | — |
| 4J5A | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | X | — | — |
| 4J5A | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | X | — | — |
| 4J5B | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | A | — | — |
| 4J5B | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | A | — | — |
| 4J5C | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | X | — | — |
| 4J5C | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | X | — | — |
| 4J5D | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | X | — | — |
| 4J5D | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | X | — | — |
| 4J5E | Human Cyclophilin D Complexed with an Inhibitor | x-ray diffraction | X | — | — |
| 4J5E | Human cyclophilin D complexed with an inhibitor | x-ray diffraction | X | — | — |
| 4O8H | 0.85A resolution structure of PEG 400 Bound Cyclophilin D | x-ray diffraction | A | — | — |
| 4O8H | 0.85A resolution structure of peg 400 bound cyclophilin D | x-ray diffraction | A | — | — |
| 4O8I | 1.45A resolution structure of PEG 400 Bound Cyclophilin D | x-ray diffraction | A | — | — |
| 4O8I | 1.45A resolution structure of peg 400 bound cyclophilin D | x-ray diffraction | A | — | — |
| 4XNC | Crystal structure at room temperature of cyclophilin D in complex with an inhibitor | x-ray diffraction | A | — | — |
| 4XNC | Crystal structure at room temperature of cyclophilin D in complex with an inhibitor | x-ray diffraction | A | — | — |
| 4ZSC | Human Cyclophilin D Complexed with an Inhibitor at room temperature | x-ray diffraction | A | EA4 | — |
| 4ZSC | Human cyclophilin D complexed with an inhibitor at room temperature | x-ray diffraction | A | — | — |
56 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 6 records
- JVQ · 14-ethyl-4,6-dioxa-10,14-diazatricyclo[7.6.0.0^{3, 7}]pentadeca-1(9),2,7-trien-13-one · in 4 records
- I3Q · (4S,7R,11S,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-4-[(furan-2-yl)methyl]-3,6,12,15,21-pentaoxo-1,3,4,5,6, 7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide · in 2 records
- I4F · (4S,7S,11R,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-7-benzyl-4-[(furan-2-yl)methyl]-3,6,12,15,21-pentaoxo-1, 3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide · in 2 records
- I5J · (4S,7S,11R,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-7-benzyl-4-[(3-methylphenyl)methyl]-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21, 22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide · in 2 records
- JVN · (1~{R},9~{R},10~{S})-4-fluoranyl-12-oxa-8-azatricyclo[7.3.1.0^{2,7}]trideca-2(7),3,5-trien-10-ol · in 2 records
- JW2 · ~{N}'-cyclopentyl-~{N}-(pyridin-2-ylmethyl) ethanediamide · in 2 records
- JWB · 2-[(1~{R},2~{R},6~{S},7~{S})-3,5-bis(oxidanylidene)-4-azatricyclo[5.2.1.0^{2,6}]decan-4-yl]ethanoic acid · in 2 records
- NA · Sodium ion · in 2 records
- VDH · N-(5-ethyl-4-oxidanylidene-1,2,3,6-tetrahydro-1,5-benzodiazocin-8-yl)-7-methyl-2-oxidanylidene-1H-pyrazolo[1,5-a]pyrimidine-6-carboxamide · in 2 records
- 4ZM · ethyl N-{[3-(pyridin-4-yl)benzyl]carbamoyl}glycinate · in 1 record
- 502 · ethyl N-{[(2-aminopyridin-4-yl)methyl]carbamoyl}glycinate · in 1 record
- 7I6 · 1-(4-aminobenzyl)-3-[(2S)-4-(methylsulfanyl)-1-{(2R)-2-[2-(methylsulfanyl)phenyl]pyrrolidin-1-yl}-1-oxobutan-2-yl]urea · in 1 record
- 7UO · ~{N}-[(5-ethyl-4-oxidanylidene-1,2,3,6-tetrahydro-1,5-benzodiazocin-8-yl)methyl]-7-methyl-2-oxidanylidene-1,3-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide · in 1 record
- 9JT · ~{N}-phenyl-2-selanyl-benzamide · in 1 record
- C4Y · 1-(4-aminobenzyl)-3-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}urea · in 1 record
- CL · Chloride ion · in 1 record
- EA4 · ethyl N-[(4-aminobenzyl)carbamoyl]glycinate · in 1 record
- I3X · (4S,7S,11R,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-7-benzyl-4-[([1,1'-biphenyl]-4-yl)methyl]-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21, 22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide · in 1 record
- I44 · (4S,7S,11R,13E,19S)-N-[2-(2-aminoethoxy)ethyl]-4-[(4-benzoylphenyl)methyl]-7-benzyl-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosine-19-carboxamide · in 1 record
- I4V · [(4'-{[(4S,7S,11R,13E,19S)-19-{[2-(2-aminoethoxy)ethyl]carbamoyl}-7-benzyl-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosin-4-yl]methyl}[1,1'-biphenyl]-4-yl)methyl]propanedioic acid · in 1 record
- I4Z · 3-(4'-{[(4S,7S,11R,13E,19S)-19-{[2-(2-aminoethoxy)ethyl]carbamoyl}-7-benzyl-3,6,12,15,21-pentaoxo-1,3,4,5,6,7,8,9,10,12,15,16,17,18,19,20,21,22-octadecahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosin-4-yl]methyl}[1,1'-biphenyl]-4-yl)prop-2-ynoic acid · in 1 record
- I5E · 3-(4'-{[(4S,7S,11R,19S)-19-{[2-(2-aminoethoxy) ethyl]carbamoyl}-7-benzyl-3,6,12,15,21-pentaoxo-1,3,4, 5,6,7,8,9,10,12,13,14,15,16,17,18,19,20,21,22-icosahydro-2H-7,11-methano-2,5,11,16,20-benzopentaazacyclotetracosin-4-yl]methyl}[1,1'-biphenyl]-4-yl)propanoic acid · in 1 record
- JUZ · 1-[2-[(2~{R})-2-(2-methylsulfanylphenyl)pyrrolidin-1-yl]-2-oxidanylidene-ethyl]-3-[[(1~{S},9~{S},10~{S})-10-oxidanyl-12-oxa-8-azatricyclo[7.3.1.0^{2, 7}]trideca-2(7),3,5-trien-4-yl]methyl]urea · in 1 record
- JVH · 2-(exo-3,5-dioxo-4-aza-tricyclo[5.2.1.02,6]dec-4-yl)-N-((1R,9R,10S)-10-hydroxy-12-oxa-8-aza-tricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ylmethyl)-acetamide · in 1 record
- K · Potassium ion · in 1 record
- O4B · 1,4,7,10,13,16-hexaoxacyclooctadecane · in 1 record
- PO4 · Phosphate ion · in 1 record
- UPZ · ethyl 7-methyl-2-oxidanylidene-1,3-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate · in 1 record
- UX5 · N-(4-aminophenyl)-7-methyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-6-carboxamide · in 1 record
Elsewhere
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