GL1X · GenesisL1 explorer

MolNFT v1 · #77379 · protein

Human cyclophilin D complexed with a fragment

3RD9 · Peptidyl-prolyl cis-trans isomerase F, mitochondrial: “Human cyclophilin D complexed with a fragment”. X-ray diffraction, 1 ligand (MSY). MolNFT v1 #77379 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3RD9
Type
protein
Length
164 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Peptidyl-prolyl cis-trans isomerase F, mitochondrial
EC
5.2.1.8
UniProt
P30405
Ligands
MSY

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 32% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
XPeptidyl-prolyl cis-trans isomerase F, mitochondrial (EC 5.2.1.8)protein16415% helix, 32% strandP30405

Ligands and binding sites

  • MSY · 3-(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide · ligand · chains X
  • PEG · Di(hydroxyethyl)ether · additive · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 3RD9 · Human Cyclophilin D Complexed with a Fragment · the same entry in another collection · chain X against X, TM-score 1.00
  • P30405 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase F… · a predicted model of the same protein · chain X against A, TM-score 1.00

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