Research workbench
Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II. structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment
Analyse Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1NGI
- Type
- protein
- Length
- 378 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat-shock cognate 70 kd protein
- EC
- 3.6.1.3
- UniProt
- P19120
- Ligands
- ANP, CA
- Pockets
- 1 · best druggability 0.78
Structure
x-ray diffraction · 1 distinct chain · 40% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat-shock cognate 70 kd protein (EC 3.6.1.3) | protein | 378 | 40% helix, 29% strand | P19120 |
Ligands and binding sites
- ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
- CA · Calcium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 755 | 0.78 | 0.82 | 78 | CA, ANP |
Compared structures
- 1NGI · Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity… · the same entry in another collection · chain A against A, TM-score 1.00
- P19120 · AlphaFold monomer V2.0 prediction for heat shock cognate 71 kda protein (P19120) · a predicted model of the same protein · chain A against A, TM-score 0.89
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P19120
- Elsewhere: RCSB PDB 1NGI · PDBe 1NGI · UniProt P19120
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