UniProt P19120
Heat shock cognate 71 kDa protein (P19120)
Heat shock cognate 71 kDa protein (UniProt P19120): 79 experimental structures and 1 predicted model on GenesisL1, 8 ligands bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P19120
- Protein
- Heat shock cognate 71 kDa protein
- Experimental structures
- 79
- Predicted models
- 1
- Ligands
- 8
- Pockets
- 6 · 1 record with a druggable one
Structures
80 records of P19120 in the MolNFT archive: 79 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ATR | Threonine 204 of the chaperone protein HSC70 influences the structure of the active site but is not… | x-ray diffraction | A | — | — |
| 1ATR | Threonine 204 of the chaperone protein HSC70 influences the structure of the active site but is not… | x-ray diffraction | A | — | — |
| 1ATS | Threonine 204 of the chaperone protein HSC70 influences the structure of the active site but is not… | x-ray diffraction | A | — | — |
| 1ATS | Threonine 204 of the chaperone protein HSC70 influences the structure of the active site but is not… | x-ray diffraction | A | — | — |
| 1BA0 | Heat-shock cognate 70KD protein 44KD ATPase N-terminal 1NGE 3 | x-ray diffraction | A | — | — |
| 1BA0 | Heat-shock cognate 70KD protein 44KD ATPase N-terminal 1NGE 3 | x-ray diffraction | A | — | — |
| 1BA1 | Heat-shock cognate 70KD protein 44KD ATPase N-terminal mutant with cys 17 replaced by lys | x-ray diffraction | A | — | — |
| 1BA1 | Heat-shock cognate 70KD protein 44KD ATPase N-terminal mutant with cys 17 replaced by lys | x-ray diffraction | A | — | — |
| 1BUP | T13S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1BUP | T13S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1HPM | How potassium affects the activity of the molecular chaperone HSC70. II. potassium binds… | x-ray diffraction | A | — | — |
| 1HPM | How potassium affects the activity of the molecular chaperone HSC70. II. potassium binds… | x-ray diffraction | A | — | — |
| 1HX1 | Crystal structure of a bag domain in complex with the HSC70 ATPase domain | x-ray diffraction | A | — | — |
| 1HX1 | Crystal structure of a bag domain in complex with the HSC70 ATPase domain | x-ray diffraction | A | — | — |
| 1KAX | 70KD heat shock cognate protein ATPase domain, K71M mutant | x-ray diffraction | A | — | — |
| 1KAX | 70KD heat shock cognate protein ATPase domain, K71M mutant | x-ray diffraction | A | — | — |
| 1KAY | 70KD heat shock cognate protein ATPase domain, K71A mutant | x-ray diffraction | A | — | — |
| 1KAY | 70KD heat shock cognate protein ATPase domain, K71A mutant | x-ray diffraction | A | — | — |
| 1KAZ | 70KD heat shock cognate protein ATPase domain, K71E mutant | x-ray diffraction | A | — | — |
| 1KAZ | 70KD heat shock cognate protein ATPase domain, K71E mutant | x-ray diffraction | A | — | — |
| 1NGA | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGA | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGB | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGB | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGC | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGC | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGD | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGD | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGE | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGE | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGF | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGF | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGG | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGG | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGH | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGH | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGI | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGI | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGJ | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1NGJ | Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity, II.… | x-ray diffraction | A | — | — |
| 1QQM | D199S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1QQM | D199S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1QQN | D206S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1QQN | D206S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1QQO | E175S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1QQO | E175S mutant of bovine 70 kilodalton heat shock protein | x-ray diffraction | A | — | — |
| 1YUW | crystal structure of bovine hsc70(aa1-554)E213A/D214A mutant | x-ray diffraction | A | — | — |
| 1YUW | Crystal structure of bovine HSC70(AA1-554)E213A/D214A mutant | x-ray diffraction | A | — | — |
| 2BUP | T13G Mutant of the ATPASE fragment of Bovine HSC70 | x-ray diffraction | A | — | — |
| 2BUP | T13G mutant of the ATPase fragment of bovine HSC70 | x-ray diffraction | A | — | — |
| 2QW9 | Crystal structure of bovine hsc70 (1-394aa)in the apo state | x-ray diffraction | A, B | — | — |
| 2QW9 | Crystal structure of bovine HSC70 (1-394AA)IN the apo state | x-ray diffraction | A, B | — | — |
| 2QWL | Crystal structure of bovine hsc70 (1-394aa)in the ADP state | x-ray diffraction | A, B | — | — |
| 2QWL | Crystal structure of bovine HSC70 (1-394AA)IN the ADP state | x-ray diffraction | A, B | — | — |
| 2QWM | Crystal structure of bovine hsc70 (1-394aa)in the ADP*Vi state | x-ray diffraction | A, B | — | — |
| 2QWM | Crystal structure of bovine HSC70 (1-394AA)IN the ADP*VI state | x-ray diffraction | A, B | — | — |
| 2QWN | Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-386aa)R171C and bovine… | x-ray diffraction | A | — | — |
| 2QWN | Crystal structure of disulfide-bond-crosslinked complex of bovine HSC70 (1-386AA)R171C and bovine… | x-ray diffraction | A | — | — |
| 2QWO | Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine… | x-ray diffraction | A | — | — |
| 2QWO | Crystal structure of disulfide-bond-crosslinked complex of bovine HSC70 (1-394AA)R171C and bovine… | x-ray diffraction | A | — | — |
20 records more on the page itself.
Ligands
- K · Potassium ion · in 4 records
- TMO · trimethylamine oxide · in 3 records
- 3FD · 4-[[(2R,3S,4R,5R)-5-[6-amino-8-[(3,4-dichlorophenyl) methylamino]purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitrile · in 2 records
- V8Q · 6-methyl-5-sulfanylidene-2H-1,2,4-triazin-3-one · in 2 records
- LZ1 · 1H-indazole · in 1 record
- NA · Sodium ion · in 1 record
- V7Z · methanesulfonamide · in 1 record
- VLS · N-[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]glycine · in 1 record
Experiment against prediction
- 2QWO chain A against the predicted model P19120: TM-score 0.90, RMSD 2.59 Å
- 2QWO chain A against the predicted model P19120: TM-score 0.90, RMSD 2.59 Å
- 2QWQ chain A against the predicted model P19120: TM-score 0.90, RMSD 2.51 Å
- 2QWQ chain A against the predicted model P19120: TM-score 0.90, RMSD 2.51 Å
- 2QWR chain A against the predicted model P19120: TM-score 0.90, RMSD 2.51 Å
- 2QWR chain A against the predicted model P19120: TM-score 0.90, RMSD 2.51 Å
- 2QWN chain A against the predicted model P19120: TM-score 0.89, RMSD 2.60 Å
- 2QWN chain A against the predicted model P19120: TM-score 0.89, RMSD 2.60 Å
- 1BA0 chain A against the predicted model P19120: TM-score 0.89, RMSD 2.61 Å
- 1BA0 chain A against the predicted model P19120: TM-score 0.89, RMSD 2.61 Å
Elsewhere
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