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Crystal structure of the cancer genomic DNA mutator APOBEC3B with loop 7 from APOBEC3G complexed with 2-hp

Analyse Crystal structure of the cancer genomic DNA mutator APOBEC3B with loop 7 from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6NFL
Type: protein
Length: 182 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA dc->du-editing enzyme apobec-3B
EC: 3.5.4.38
UniProt: Q9UH17
Ligands: L60, 71O, CL

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA dc->du-editing enzyme apobec-3B (EC 3.5.4.38)	protein	182	38% helix, 25% strand	Q9UH17

Ligands and binding sites

L60 · 1,3-diazinan-2-one · ligand · chains A
71O · pyrimidin-2-ol · ligand · chains A
CL · Chloride ion · ion · chains A
EDO · 1,2-ethanediol · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6NFL · Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G… · the same entry in another collection · chain A against A, TM-score 1.00
Q9UH17 · AlphaFold monomer V2.0 prediction for DNA dc->du-editing enzyme apobec-3B (Q9UH17) · a predicted model of the same protein · chain A against A, TM-score 0.95

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UH17
Elsewhere: RCSB PDB 6NFL · PDBe 6NFL · UniProt Q9UH17

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