UniProt Q9UH17
DNA dC->dU-editing enzyme APOBEC-3B (Q9UH17)
DNA dC->dU-editing enzyme APOBEC-3B (UniProt Q9UH17), EC 3.5.4.-, 3.5.4.38: 22 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9UH17
- Protein
- DNA dC->dU-editing enzyme APOBEC-3B
- EC
- 3.5.4.-, 3.5.4.38
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 4 · 1 record with a druggable one
Structures
23 records of Q9UH17 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NBQ | NMR Structure of the C-Terminal Domain of human APOBEC3B | solution nmr | A | — | — |
| 2NBQ | NMR structure of the C-terminal domain of human APOBEC3B | solution nmr | A | — | — |
| 5CQD | Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B | x-ray diffraction | A, C | ZN | 1 (best 0.73) |
| 5CQD | Crystal structure of the cancer genomic DNA mutator APOBEC3B | x-ray diffraction | A, C | — | — |
| 5CQH | Crystal structure of the cancer genomic DNA mutator APOBEC3B | x-ray diffraction | A | — | — |
| 5CQI | Crystal structure of the cancer genomic DNA mutator APOBEC3B | x-ray diffraction | A | — | — |
| 5CQK | Crystal structure of the cancer genomic DNA mutator APOBEC3B | x-ray diffraction | A | — | — |
| 5SXG | Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B | x-ray diffraction | A, B | ZN | 1 (best 0.33) |
| 5SXG | Crystal structure of the cancer genomic DNA mutator APOBEC3B | x-ray diffraction | A, B | ZN | — |
| 5SXH | Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B | x-ray diffraction | A, B | ZN | 1 (best 0.32) |
| 5SXH | Crystal structure of the cancer genomic DNA mutator APOBEC3B | x-ray diffraction | A, B | ZN | — |
| 5TD5 | Crystal structure of human APOBEC3B variant complexed with ssdna | x-ray diffraction | A | ZN, IOD, CL | — |
| 5TKM | Crystal structure of human APOBEC3B N-terminal Domain | x-ray diffraction | A, B | ZN | 1 (best 0.46) |
| 5TKM | Crystal structure of human APOBEC3B N-terminal domain | x-ray diffraction | A, B | ZN | — |
| 6NFK | Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G bound to… | x-ray diffraction | A | IOD | — |
| 6NFK | Crystal structure of the cancer genomic DNA mutator APOBEC3B with loop 7 from APOBEC3G bound to… | x-ray diffraction | A | IOD | — |
| 6NFL | Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G complexed… | x-ray diffraction | A | L60, 71O, CL | — |
| 6NFL | Crystal structure of the cancer genomic DNA mutator APOBEC3B with loop 7 from APOBEC3G complexed… | x-ray diffraction | A | L60, 71O, CL | — |
| 6NFM | Crystal Structure of the Cancer Genomic DNA Mutator APOBEC3B with loop 7 from APOBEC3G | x-ray diffraction | A | CL | — |
| 6NFM | Crystal structure of the cancer genomic DNA mutator APOBEC3B with loop 7 from APOBEC3G | x-ray diffraction | A | CL | — |
| 7RW6 | BORF2-APOBEC3Bctd Complex | electron microscopy | B, D | ZN | — |
| 7RW6 | BORF2-APOBEC3BCTD complex | electron microscopy | B, D | ZN | — |
| Q9UH17 | AlphaFold monomer V2.0 prediction for DNA dc->du-editing enzyme apobec-3B (Q9UH17) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5CQK chain A against the predicted model Q9UH17: TM-score 0.98, RMSD 0.73 Å
- 5SXG chain B against the predicted model Q9UH17: TM-score 0.98, RMSD 0.79 Å
- 5SXG chain B against the predicted model Q9UH17: TM-score 0.98, RMSD 0.79 Å
- 5SXH chain B against the predicted model Q9UH17: TM-score 0.98, RMSD 0.82 Å
- 7RW6 chain D against the predicted model Q9UH17: TM-score 0.98, RMSD 0.80 Å
- 7RW6 chain D against the predicted model Q9UH17: TM-score 0.98, RMSD 0.80 Å
- 5SXH chain B against the predicted model Q9UH17: TM-score 0.98, RMSD 0.83 Å
- 7RW6 chain B against the predicted model Q9UH17: TM-score 0.98, RMSD 0.80 Å
- 7RW6 chain B against the predicted model Q9UH17: TM-score 0.98, RMSD 0.80 Å
- 5CQD chain C against the predicted model Q9UH17: TM-score 0.98, RMSD 0.89 Å
Elsewhere
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