Methylmalonyl-CoA decarboxylase in complex with 2-sulfonate-propionyl- OXA(DETHIA)-CoA

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• LCV · (2~{S})-1-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R}, 5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethoxy]-1-oxidanylidene-propane-2-sulfonic acid · ligand · 8 copies · chains A, B, C, D, E, F
• SO5 · (2~{R})-1-[2-[3-[[(2~{R})-4-[[[(2~{R},3~{S},4~{R}, 5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-3,3-dimethyl-2-oxidanyl-butanoyl]amino]propanoylamino]ethoxy]-1-oxidanylidene-propane-2-sulfonic acid · ligand · 6 copies · chains A, B, C, D, E, F
• IMD · Imidazole · additive · chains D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6N96 · Methylmalonyl-CoA decarboxylase in complex with 2-sulfonate-propionyl-oxa(dethia)-CoA · the same entry in another collection · chain C against C, TM-score 1.00
• P52045 · AlphaFold monomer V2.0 prediction for methylmalonyl-CoA decarboxylase (P52045) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P52045
• Elsewhere: RCSB PDB 6N96 · PDBe 6N96 · UniProt P52045