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Crystal structure of HIV-1 BG505 SOSIP.664 prefusion env trimer bound to small molecule HIV-1 entry inhibitor compound 484 in complex with human antibodies 3H109L and 35O22 at 3.0 ångström

Analyse Crystal structure of HIV-1 BG505 SOSIP.664 prefusion env trimer bound to small… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6MTN
Type: protein
Length: 1,237 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q2N0S6
Ligands: JYJ, NAG, MAN, BMA

Structure

x-ray diffraction · 6 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	—	protein	128	—	Q2N0S6
D	—	protein	128	—	—
E	—	protein	105	—	—
G	—	protein	439	—	Q2N0S6
H	—	protein	226	—	—
L	—	protein	211	—	—

Ligands and binding sites

JYJ · {4-[1-(3-chlorophenyl)cyclopropane-1-carbonyl]piperazin-1-yl}(thiophen-3-yl)methanone · ligand · chains G
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 27 copies · chains D, B, G, H, E
MAN · alpha-D-mannopyranose · sugar · 10 copies · chains D, E, H, L
BMA · beta-D-mannopyranose · sugar · 4 copies · chains D, E, H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6MTN · Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule… · the same entry in another collection · chain B against B, TM-score 1.00

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Every structure of UniProt Q2N0S6
Elsewhere: RCSB PDB 6MTN · PDBe 6MTN · UniProt Q2N0S6

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