Research workbench
Crystal structure of trkc in complex with 3-(IMIDAZO[1,2-A]PYRAZIN-3- ylethynyl)-2-methyl-N-(3-((4- methylpiperazin-1-YL)METHYL)-5- (TRIFLUOROMETHYL)PHENYL)BENZAMIDE
Analyse Crystal structure of trkc in complex with 3-(IMIDAZO[1,2-A]PYRAZIN-3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6KZC
- Type
- protein
- Length
- 281 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q16288
- Ligands
- DZC
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 281 | — | Q16288 |
Ligands and binding sites
- DZC · 3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl) phenyl]benzamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6KZC · crystal structure of TRKc in complex with 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-N… · the same entry in another collection · chain A against A, TM-score 1.00
- Q16288 · AlphaFold monomer V2.0 prediction for nt-3 growth factor receptor (Q16288) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16288
- Elsewhere: RCSB PDB 6KZC · PDBe 6KZC · UniProt Q16288
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