Crystal structure of REV7(R124A/A135D) in complex with a SHIELDIN3 fragment

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 28% strand (DSSP).

Ligands and binding sites

• SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1172 Ų buried · 11 hydrogen bonds · protein-protein

Compared structures

• 6K08 · Crystal structure of REV7(R124A/A135D) in complex with a Shieldin3 fragment · the same entry in another collection · chain A against A, TM-score 1.00
• Q9UI95 · AlphaFold monomer V2.0 prediction for mitotic spindle assembly checkpoint protein MAD2B… · a predicted model of the same protein · chain A against A, TM-score 0.97
• Q6ZNX1 · AlphaFold monomer V2.0 prediction for shieldin complex subunit 3 (Q6ZNX1) · a predicted model of the same protein · chain B against A, TM-score 0.51

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9UI95
• Every structure of UniProt Q6ZNX1
• Elsewhere: RCSB PDB 6K08 · PDBe 6K08 · UniProt Q9UI95 · UniProt Q6ZNX1