UniProt Q9UI95
Mitotic spindle assembly checkpoint protein MAD2B (Q9UI95)
Mitotic spindle assembly checkpoint protein MAD2B (UniProt Q9UI95), EC 2.7.7.7: 32 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against…
- UniProt
- Q9UI95
- Protein
- Mitotic spindle assembly checkpoint protein MAD2B
- EC
- 2.7.7.7
- Experimental structures
- 32
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
33 records of Q9UI95 in the MolNFT archive: 32 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3ABD | Structure of human REV7 in complex with a human REV3 fragment in a monoclinic crystal | x-ray diffraction | A, B | — | — |
| 3ABD | Structure of human REV7 in complex with a human REV3 fragment in a monoclinic crystal | x-ray diffraction | A, B | — | — |
| 3ABE | Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal | x-ray diffraction | C | — | — |
| 3ABE | Structure of human REV7 in complex with a human REV3 fragment in a tetragonal crystal | x-ray diffraction | C | — | — |
| 3VU7 | Crystal structure of REV1-REV7-REV3 ternary complex | x-ray diffraction | C | — | — |
| 3VU7 | Crystal structure of REV1-REV7-REV3 ternary complex | x-ray diffraction | C | — | — |
| 4EXT | Structure of polymerase-interacting domain of human Rev1 in complex with translesional synthesis… | x-ray diffraction | C | — | — |
| 4EXT | Structure of polymerase-interacting domain of human REV1 in complex with translesional synthesis… | x-ray diffraction | C | — | — |
| 4GK0 | Crystal structure of human Rev3-Rev7-Rev1 complex | x-ray diffraction | A, B | — | — |
| 4GK0 | Crystal structure of human REV3-REV7-REV1 complex | x-ray diffraction | A, B | — | — |
| 4GK5 | Crystal structure of human Rev3-Rev7-Rev1-Polkappa complex | x-ray diffraction | A, B | — | — |
| 4GK5 | Crystal structure of human REV3-REV7-REV1-polkappa complex | x-ray diffraction | A, B | — | — |
| 5XPT | Crystal structure of MAD2L2/REV7 in complex with a CAMP fragment in a tetragonal crystal | x-ray diffraction | A | — | — |
| 5XPT | Crystal structure of MAD2L2/REV7 in complex with a camp fragment in a tetragonal crystal | x-ray diffraction | A | — | — |
| 5XPU | Crystal structure of MAD2L2/REV7 in complex with a camp fragment in a monoclinic crystal | x-ray diffraction | A | — | — |
| 6BC8 | Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex | x-ray diffraction | A | SO4 | — |
| 6BC8 | Crystal structure of REV7-R124A/REV3-RBM2 (residues 1988-2014) complex | x-ray diffraction | A | SO4 | — |
| 6BCD | Crystal structure of REV7-K44A/R124A/A135D in complex with REV3-RBM2 (residues 1988-2014) | x-ray diffraction | A | — | — |
| 6BI7 | Crystal structure of REV7-WT/REV3 as a monomer under high-salt conditions | x-ray diffraction | A, C, E, G | — | — |
| 6K07 | Crystal structure of REV7(R124A) in complex with a SHIELDIN3 fragment | x-ray diffraction | A | SO4 | — |
| 6K08 | Crystal structure of REV7(R124A/A135D) in complex with a Shieldin3 fragment | x-ray diffraction | A | SO4 | — |
| 6K08 | Crystal structure of REV7(R124A/A135D) in complex with a SHIELDIN3 fragment | x-ray diffraction | A | SO4 | — |
| 6KEA | Crystal structure of mbp-tagged REV7-ipab complex | x-ray diffraction | A, B, C, D | — | — |
| 6KTO | Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex | x-ray diffraction | A, B | — | — |
| 6M7A | Structure of REV7-R124A complexed with SHLD3(28-73) | x-ray diffraction | A, B | — | — |
| 6M7B | Structure of REV7-R124A complexed with SHLD3(37-73) | x-ray diffraction | A, B | — | — |
| 6NIF | crystal structure of human REV7-RAN complex | x-ray diffraction | A | — | 1 (best 0.40) |
| 6NIF | Crystal structure of human REV7-ran complex | x-ray diffraction | A | — | — |
| 6VE5 | X-ray structure of human REV7 in complex with SHIELDIN3 (residues 41- 74) | x-ray diffraction | A | SO4 | — |
| 6WW9 | Crystal structure of human REV7(R124A)-SHLD3(35-58) complex | x-ray diffraction | A, B | — | — |
| 6WWA | Crystal structure of human SHLD2-SHLD3-REV7 complex | x-ray diffraction | A, D, C, B | — | — |
| 7L9P | Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex | electron microscopy | G, I, J, K | — | — |
| Q9UI95 | AlphaFold monomer V2.0 prediction for mitotic spindle assembly checkpoint protein MAD2B (Q9UI95) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 6 records
Experiment against prediction
- 3ABD chain A against the predicted model Q9UI95: TM-score 0.99, RMSD 0.68 Å
- 3ABD chain A against the predicted model Q9UI95: TM-score 0.99, RMSD 0.68 Å
- 3VU7 chain C against the predicted model Q9UI95: TM-score 0.98, RMSD 0.74 Å
- 3VU7 chain C against the predicted model Q9UI95: TM-score 0.98, RMSD 0.74 Å
- 6M7A chain B against the predicted model Q9UI95: TM-score 0.98, RMSD 0.80 Å
- 3ABE chain C against the predicted model Q9UI95: TM-score 0.98, RMSD 0.82 Å
- 3ABE chain C against the predicted model Q9UI95: TM-score 0.98, RMSD 0.82 Å
- 4GK0 chain B against the predicted model Q9UI95: TM-score 0.98, RMSD 0.78 Å
- 4GK0 chain B against the predicted model Q9UI95: TM-score 0.98, RMSD 0.78 Å
- 6M7B chain B against the predicted model Q9UI95: TM-score 0.98, RMSD 0.86 Å
Elsewhere
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