UniProt Q6ZNX1
Shieldin complex subunit 3 (Q6ZNX1)
Shieldin complex subunit 3 (UniProt Q6ZNX1): 18 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 32 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6ZNX1
- Protein
- Shieldin complex subunit 3
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 32 · 5 records with a druggable one
Structures
19 records of Q6ZNX1 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K07 | Crystal structure of REV7(R124A) in complex with a Shieldin3 fragment | x-ray diffraction | B | — | 1 (best 0.26) |
| 6K07 | Crystal structure of REV7(R124A) in complex with a SHIELDIN3 fragment | x-ray diffraction | B | — | — |
| 6K08 | Crystal structure of REV7(R124A/A135D) in complex with a Shieldin3 fragment | x-ray diffraction | B | — | — |
| 6K08 | Crystal structure of REV7(R124A/A135D) in complex with a SHIELDIN3 fragment | x-ray diffraction | B | — | — |
| 6KTO | Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex | x-ray diffraction | C | — | 3 (best 0.44) |
| 6KTO | Crystal structure of human SHLD3-C-REV7-O-REV7-SHLD2 complex | x-ray diffraction | C | — | — |
| 6M7A | Structure of REV7-R124A complexed with SHLD3(28-73) | x-ray diffraction | D, C | — | 4 (best 0.82) |
| 6M7A | Structure of REV7-R124A complexed with SHLD3(28-73) | x-ray diffraction | D, C | — | — |
| 6M7B | Structure of REV7-R124A complexed with SHLD3(37-73) | x-ray diffraction | C, D | — | 5 (best 0.82) |
| 6M7B | Structure of REV7-R124A complexed with SHLD3(37-73) | x-ray diffraction | C, D | — | — |
| 6VE5 | X-ray structure of human REV7 in complex with Shieldin3 (residues 41-74) | x-ray diffraction | B | SO4 | 1 (best 0.40) |
| 6VE5 | X-ray structure of human REV7 in complex with SHIELDIN3 (residues 41- 74) | x-ray diffraction | B | SO4 | — |
| 6WW9 | Crystal structure of human REV7(R124A)-SHLD3(35-58) complex | x-ray diffraction | X, Y | — | 2 (best 0.70) |
| 6WW9 | Crystal structure of human REV7(R124A)-SHLD3(35-58) complex | x-ray diffraction | X, Y | — | — |
| 6WWA | Crystal structure of human SHLD2-SHLD3-REV7 complex | x-ray diffraction | Y, X | — | 12 (best 0.79) |
| 6WWA | Crystal structure of human SHLD2-SHLD3-REV7 complex | x-ray diffraction | Y, X | — | — |
| 7L9P | Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex | electron microscopy | Y, X | — | 4 (best 0.85) |
| 7L9P | Structure of human SHLD2-SHLD3-REV7-TRIP13(E253Q) complex | electron microscopy | Y, X | — | — |
| Q6ZNX1 | AlphaFold monomer V2.0 prediction for shieldin complex subunit 3 (Q6ZNX1) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 6KTO chain C against the predicted model Q6ZNX1: TM-score 0.79, RMSD 1.62 Å
- 6KTO chain C against the predicted model Q6ZNX1: TM-score 0.79, RMSD 1.62 Å
- 7L9P chain Y against the predicted model Q6ZNX1: TM-score 0.64, RMSD 2.02 Å
- 7L9P chain Y against the predicted model Q6ZNX1: TM-score 0.64, RMSD 2.02 Å
- 6WW9 chain X against the predicted model Q6ZNX1: TM-score 0.64, RMSD 0.70 Å
- 6WW9 chain X against the predicted model Q6ZNX1: TM-score 0.64, RMSD 0.70 Å
- 6WWA chain Y against the predicted model Q6ZNX1: TM-score 0.62, RMSD 2.44 Å
- 6WWA chain Y against the predicted model Q6ZNX1: TM-score 0.62, RMSD 2.44 Å
- 7L9P chain X against the predicted model Q6ZNX1: TM-score 0.62, RMSD 2.25 Å
- 7L9P chain X against the predicted model Q6ZNX1: TM-score 0.62, RMSD 2.25 Å
Elsewhere
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