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Crystal structure of plasmodium falciparum hppk-dhps A437G with stz- dhp
Analyse Crystal structure of plasmodium falciparum hppk-dhps A437G with stz- dhp in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6JWV
- Type
- protein
- Length
- 1,083 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q25704
- Ligands
- XTZ, PH2, ATP, MG, CA
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 543 | — | Q25704 |
| B | — | protein | 540 | — | Q25704 |
Ligands and binding sites
- XTZ · 4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl) methyl]amino}-N-(1,3-thiazol-2-yl)benzenesulfonamide · ligand · 2 copies · chains A, B
- PH2 · 2-amino-6-hydroxymethyl-7,8-dihydro-3H-pteridin-4-one · ligand · chains A
- ATP · Adenosine-5'-triphosphate · ligand · chains A
- MG · Magnesium ion · metal · 3 copies · chains A, B
- CA · Calcium ion · metal · 2 copies · chains A, B
- ACT · Acetate ion · additive · 4 copies · chains A, B
- GOL · Glycerol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6JWV · Crystal structure of Plasmodium falciparum HPPK-DHPS A437G with STZ-DHP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q25704
- Elsewhere: RCSB PDB 6JWV · PDBe 6JWV · UniProt Q25704
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