Research workbench
Crystal structure of the spry domain of SPSB2 in complex with CR7, a potent cyclic peptide inhibitor of SPSB2-inos interaction
Analyse Crystal structure of the spry domain of SPSB2 in complex with CR7, a potent… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6JWM
- Type
- protein
- Length
- 210 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spry domain-containing socs box protein 2; Nitric oxide synthase, inducible
- EC
- 1.14.13.39
- UniProt
- Q99619, P35228
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spry domain-containing socs box protein 2 | protein | 203 | 11% helix, 40% strand | Q99619 |
| B | Nitric oxide synthase, inducible (EC 1.14.13.39) | protein | 7 | 0% helix, 0% strand | P35228 |
Interfaces
1 interface between chains.
- A–B · 344 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 6JWM · Crystal structure of the SPRY domain of SPSB2 in complex with cR7, a potent cyclic… · the same entry in another collection · chain A against A, TM-score 1.00
- Q99619 · AlphaFold monomer V2.0 prediction for spry domain-containing socs box protein 2 (Q99619) · a predicted model of the same protein · chain A against A, TM-score 0.97
- P35228 · AlphaFold monomer V2.0 prediction for nitric oxide synthase, inducible (P35228) · a predicted model of the same protein · chain B against A, TM-score 0.44
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99619
- Every structure of UniProt P35228
- Elsewhere: RCSB PDB 6JWM · PDBe 6JWM · UniProt Q99619 · UniProt P35228
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