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Crystal structure of the dts-motif rhodopsin from phaeocystis globosa virus 12T

Analyse Crystal structure of the dts-motif rhodopsin from phaeocystis globosa virus 12T in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6JO0
Type
protein
Length
224 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Virrdts
UniProt
G8DI69
Ligands
RET, D10, D12, OLB, PO4
Pockets
2 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 83% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AVirrdtsprotein22483% helix, 0% strandG8DI69

Ligands and binding sites

  • RET · Retinal · ligand · chains A
  • D10 · Decane · ligand · chains A
  • D12 · Dodecane · ligand · chains A
  • OLB · (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · ligand · chains A
  • PO4 · Phosphate ion · ion · chains A
  • OCT · N-octane · additive · 6 copies · chains A
  • HEX · Hexane · additive · 5 copies · chains A
  • DD9 · nonane · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11530.810.9726RET
2960.500.8117OCT, OLB

Modifications

Observed in the structure: 1 cofactor (retinal Schiff base).

Compared structures

  • 6JO0 · Crystal structure of the DTS-motif rhodopsin from Phaeocystis globosa virus 12T · the same entry in another collection · chain A against A, TM-score 1.00

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