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Co-crystal structure of human spop math domain (wild-type) and human BRD3 fragment

Analyse Co-crystal structure of human spop math domain (wild-type) and human BRD3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6I41
Type: protein
Length: 146 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Speckle-type poz protein; Bromodomain-containing protein 3
UniProt: O43791, Q15059

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 51% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Speckle-type poz protein	protein	139	14% helix, 53% strand	O43791
B	Bromodomain-containing protein 3	protein	7	0% helix, 14% strand	Q15059

Interfaces

1 interface between chains.

A–B · 378 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

6I41 · Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment · the same entry in another collection · chain A against A, TM-score 1.00
O43791 · AlphaFold monomer V2.0 prediction for speckle-type poz protein (O43791) · a predicted model of the same protein · chain A against A, TM-score 0.94
Q15059 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 3 (Q15059) · a predicted model of the same protein · chain B against A, TM-score 0.39

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43791
Every structure of UniProt Q15059
Elsewhere: RCSB PDB 6I41 · PDBe 6I41 · UniProt O43791 · UniProt Q15059

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