UniProt O43791
Speckle-type POZ protein (O43791)
Speckle-type POZ protein (UniProt O43791): 48 experimental structures on GenesisL1, 2 ligands bound, 33 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O43791
- Protein
- Speckle-type POZ protein
- Experimental structures
- 48
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 33 · 3 records with a druggable one
Structures
48 records of O43791 in the MolNFT archive: 48 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CR2 | Solution structure of N-terminal domain of speckle-type POZ protein | solution nmr | A | — | — |
| 2CR2 | Solution structure of N-terminal domain of speckle-type poz protein | solution nmr | A | — | — |
| 3HQH | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A | — | — |
| 3HQI | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HQI | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HQL | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HQL | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HQM | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HQM | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HSV | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HSV | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HTM | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B, C, D | — | — |
| 3HTM | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B, C, D | — | — |
| 3HU6 | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B | — | — |
| 3HU6 | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B | — | — |
| 3IVB | Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases… | x-ray diffraction | A | — | — |
| 3IVB | Structures of spop-substrate complexes: insights into architectures of btb-CUL3 ubiquitin ligases… | x-ray diffraction | A | — | — |
| 3IVQ | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A, B | — | — |
| 3IVQ | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A, B | — | — |
| 3IVV | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin… | x-ray diffraction | A | — | — |
| 3IVV | Structures of spop-substrate complexes: insights into molecular architectures of btb-CUL3 ubiquitin… | x-ray diffraction | A | — | — |
| 4EOZ | Crystal structure of the SPOP BTB domain complexed with the Cul3 N-terminal domain | x-ray diffraction | A, C | — | — |
| 4EOZ | Crystal structure of the spop btb domain complexed with the CUL3 N- terminal domain | x-ray diffraction | A, C | — | — |
| 4HS2 | Crystal Structure of the Human SPOP C-terminal Domain | x-ray diffraction | A | — | — |
| 4HS2 | Crystal structure of the human spop C-terminal domain | x-ray diffraction | A | — | — |
| 4J8Z | Crystal Structure of the Human SPOP BTB Domain | x-ray diffraction | A, B | — | — |
| 4J8Z | Crystal structure of the human spop btb domain | x-ray diffraction | A, B | — | — |
| 4O1V | SPOP Promotes Tumorigenesis by Acting as a Key Regulatory Hub in Kidney Cancer | x-ray diffraction | A | — | — |
| 4O1V | Spop promotes tumorigenesis by acting as a key regulatory hub in kidney cancer | x-ray diffraction | A | — | — |
| 6F8F | Co-crystal structure of spop math domain and human PDX1 fragment | x-ray diffraction | D | — | — |
| 6F8G | Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment | x-ray diffraction | A, B, C, D | — | 6 (best 0.80) |
| 6F8G | Co-crystal structure of spop math domain and hamster PDX1 fragment | x-ray diffraction | A, B, C, D | — | — |
| 6I41 | Co-crystal structure of human SPOP MATH domain (wild-type) and human BRD3 fragment | x-ray diffraction | A | — | — |
| 6I41 | Co-crystal structure of human spop math domain (wild-type) and human BRD3 fragment | x-ray diffraction | A | — | — |
| 6I5P | Co-crystal structure of human spop math domain (E47K) and human BRD3 fragment | x-ray diffraction | A, C, E, G | — | — |
| 6I68 | Co-crystal structure of human spop math domain (M117V) and human BRD3 fragment | x-ray diffraction | A, C, E, G | — | — |
| 6I7A | Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment | x-ray diffraction | A, C, E, G | — | 4 (best 0.47) |
| 6I7A | Co-crystal structure of human spop math domain (D140N) and human BRD3 fragment | x-ray diffraction | A, C, E, G | — | — |
| 7D3D | Crystal structure of SPOP bound with a peptide | x-ray diffraction | A, B | — | 3 (best 0.73) |
| 7D3D | Crystal structure of spop bound with a peptide | x-ray diffraction | A, B | — | — |
| 7KLZ | Structure of spop math domain in complex with a geminin peptide | x-ray diffraction | A, B | PO4 | — |
| 7LIN | X-ray structure of spop math domain (D140G) in complex with a 53BP1 peptide | x-ray diffraction | A | SO4 | — |
| 7LIO | X-ray structure of SPOP MATH domain (S119D) in complex with a 53BP1 peptide | x-ray diffraction | A, B | — | — |
| 7LIO | X-ray structure of spop math domain (S119D) in complex with a 53BP1 peptide | x-ray diffraction | A, B | — | — |
| 7LIP | X-ray structure of spop math domain (D140G) | x-ray diffraction | A | SO4 | — |
| 7LIQ | X-ray structure of spop math domain (S119A) | x-ray diffraction | A | — | — |
| 8DWT | SPOP W22R Form 2 | electron microscopy | C, D, A, B, G, H, J, K, I, F, L, E | — | 20 (best 0.82) |
| O43791 | AlphaFold monomer V2.0 prediction for speckle-type poz protein (O43791) | — | — | — |
Ligands
Elsewhere
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