Research workbench
Structure of the DDB1-crbn-pomalidomide complex bound to ZNF692(ZF4)
Analyse Structure of the DDB1-crbn-pomalidomide complex bound to ZNF692(ZF4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6H0G
- Type
- protein
- Length
- 2,512 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q16531, Q96SW2, Q9BU19
- Ligands
- Y70, ZN
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | — | protein | 825 | — | Q16531 |
| B, E | — | protein | 401 | — | Q96SW2 |
| C, F | — | protein | 30 | — | Q9BU19 |
Ligands and binding sites
- Y70 · S-Pomalidomide · ligand · 2 copies · chains B, C, E, F
- ZN · Zinc ion · metal · 4 copies · chains B, C, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6H0G · Structure of the DDB1-CRBN-pomalidomide complex bound to ZNF692(ZF4) · the same entry in another collection · chain F against F, TM-score 1.00
- Q16531 · AlphaFold monomer V2.0 prediction for DNA damage-binding protein 1 (Q16531) · a predicted model of the same protein · chain D against A, TM-score 0.98
- Q96SW2 · AlphaFold monomer V2.0 prediction for protein cereblon (Q96SW2) · a predicted model of the same protein · chain B against A, TM-score 0.98
- Q9BU19 · AlphaFold monomer V2.0 prediction for zinc finger protein 692 (Q9BU19) · a predicted model of the same protein · chain C against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16531
- Every structure of UniProt Q96SW2
- Every structure of UniProt Q9BU19
- Elsewhere: RCSB PDB 6H0G · PDBe 6H0G · UniProt Q16531 · UniProt Q96SW2 · UniProt Q9BU19
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