Structure of fully reduced variant E28Q of E. COLI hydrogenase-1 at pH 8

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• SF4 · Iron/sulfur cluster · ligand · 2 copies · chains S, T
• F3S · FE3-S4 cluster · ligand · 2 copies · chains S, L, T, M
• SF3 · FE4-S3 cluster · ligand · 2 copies · chains S, L, T, M
• EJ2 · Ni-Fe reduced active center · ligand · 2 copies · chains L, M
• MG · Magnesium ion · metal · 2 copies · chains L, M
• CL · Chloride ion · ion · 4 copies · chains S, T
• SO4 · Sulfate ion · ion · chains S, L
• LMT · Dodecyl-beta-D-maltoside · additive · 2 copies · chains S, T

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6G7R · Structure of fully reduced variant E28Q of E. coli hydrogenase-1 at pH 8 · the same entry in another collection · chain S against S, TM-score 1.00
• P0ACD8 · AlphaFold monomer V2.0 prediction for hydrogenase-1 large chain (P0ACD8) · a predicted model of the same protein · chain L against A, TM-score 1.00
• P69739 · AlphaFold monomer V2.0 prediction for hydrogenase-1 small chain (P69739) · a predicted model of the same protein · chain S against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P69739
• Every structure of UniProt P0ACD8
• Elsewhere: RCSB PDB 6G7R · PDBe 6G7R · UniProt P69739 · UniProt P0ACD8