Research workbench
Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor 93-97
Analyse Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6E7X
- Type
- protein
- Length
- 1,441 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- A0A1L8F5J9, Q00960
- Ligands
- T97, NAG, MAN, BMA, NA, CL
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 358 | — | A0A1L8F5J9 |
| B, D | — | protein | 363 | — | Q00960 |
| C | — | protein | 357 | — | A0A1L8F5J9 |
Ligands and binding sites
- T97 · N-{4-[(2S)-3-{[2-(3,4-dichlorophenyl)ethyl](2-methylpropyl)amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · ligand · 2 copies · chains A, B, C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 8 copies · chains A, B, C, D
- MAN · alpha-D-mannopyranose · sugar · 2 copies
- BMA · beta-D-mannopyranose · sugar
- NA · Sodium ion · metal · 2 copies · chains A, C
- CL · Chloride ion · ion · 9 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6E7X · Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric… · the same entry in another collection · chain A against A, TM-score 1.00
- Q00960 · AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 2B (Q00960) · a predicted model of the same protein · chain B against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1L8F5J9
- Every structure of UniProt Q00960
- Elsewhere: RCSB PDB 6E7X · PDBe 6E7X · UniProt A0A1L8F5J9 · UniProt Q00960
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