UniProt A0A1L8F5J9
Glutamate receptor ionotropic, NMDA 1 (A0A1L8F5J9)
Glutamate receptor ionotropic, NMDA 1 (UniProt A0A1L8F5J9): 11 experimental structures and 1 predicted model on GenesisL1, 11 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- A0A1L8F5J9
- Protein
- Glutamate receptor ionotropic, NMDA 1
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 11
- Pockets
- 17 · 2 records with a druggable one
Structures
12 records of A0A1L8F5J9 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6E7R | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HYS | — |
| 6E7S | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HZ4 | — |
| 6E7T | Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HYY | 8 (best 0.77) |
| 6E7T | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HYY | — |
| 6E7U | Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HX7 | 9 (best 0.77) |
| 6E7U | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HX7 | — |
| 6E7V | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, T88 | — |
| 6E7W | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, HXM | — |
| 6E7X | Heterodimer of the GLUN1B-GLUN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, CL, T97 | — |
| 7TE6 | Crystal structure of GLUN1B-2B atd complexed to FAB5 anti-GLUN2B antibody | x-ray diffraction | A, E | — | — |
| 8G18 | Heterodimer of the GluN1b-GluN2B NMDA receptor amino-terminal domains bound to allosteric inhibitor… | x-ray diffraction | A, C | NAG, NA, YGW | — |
| A0A1L8F5J9 | AlphaFold monomer V2.0 prediction for glutamate receptor ionotropic, NMDA 1 (A0A1L8F5J9) | predicted | — | — |
Ligands
- NA · Sodium ion · in 10 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 10 records
- CL · Chloride ion · in 9 records
- HX7 · N-{4-[(2S)-3-{butyl[2-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 2 records
- HYY · N-{4-[(2S)-3-{[2-(3,4-dichlorophenyl)ethyl](propyl) amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 2 records
- HXM · N-{4-[(2S)-3-{[2-(3,4-dichlorophenyl)ethyl](propan-2-yl)amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 1 record
- HYS · N-{4-[(2S)-3-{[2-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 1 record
- HZ4 · N-{4-[(2S)-3-{[2-(3,4-dichlorophenyl)ethyl](ethyl) amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 1 record
- T88 · N-{4-[(2R)-3-{butyl[2-(3,4-dichlorophenyl)ethyl]amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 1 record
- T97 · N-{4-[(2S)-3-{[2-(3,4-dichlorophenyl)ethyl](2-methylpropyl)amino}-2-hydroxypropoxy]phenyl}methanesulfonamide · in 1 record
- YGW · N-(4-{3-[4-(3,4-difluorophenyl)piperazin-1-yl]-2-oxopropoxy}phenyl)methanesulfonamide · in 1 record
Elsewhere
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