Research workbench

Platelet integrin alfaiib-BETA3 cytoplasmic domain

Analyse Platelet integrin alfaiib-BETA3 cytoplasmic domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1M8O
Type: protein
Length: 67 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Platelet integrin alfaiib subunit: cytoplasmic domain; Platelet integrin BETA3 subunit…
UniProt: P08514, P05106

Structure

solution nmr · 2 distinct chains · 33% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Platelet integrin alfaiib subunit: cytoplasmic domain	protein	20	20% helix, 0% strand	P08514
B	Platelet integrin BETA3 subunit: cytoplasmic domain	protein	47	38% helix, 0% strand	P05106

Interfaces

1 interface between chains.

A–B · 241 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

1M8O · Platelet integrin alfaIIb-beta3 cytoplasmic domain · the same entry in another collection · chain A against A, TM-score 1.00
P05106 · AlphaFold monomer V2.0 prediction for integrin beta-3 (P05106) · a predicted model of the same protein · chain B against A, TM-score 0.47
P08514 · AlphaFold monomer V2.0 prediction for integrin alpha-iib (P08514) · a predicted model of the same protein · chain A against A, TM-score 0.22

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08514
Every structure of UniProt P05106
Elsewhere: RCSB PDB 1M8O · PDBe 1M8O · UniProt P08514 · UniProt P05106

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