Research workbench
Vioc L-arginine hydroxylase bound to FE(II), L-arginine, and succinate
Analyse Vioc L-arginine hydroxylase bound to FE(II), L-arginine, and succinate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ALQ
- Type
- protein
- Length
- 337 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Alpha-ketoglutarate-dependent L-arginine hydroxylase
- EC
- 1.14.11.41
- UniProt
- Q6WZB0
- Ligands
- ARG, FE2
- Pockets
- 5 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-ketoglutarate-dependent L-arginine hydroxylase (EC 1.14.11.41) | protein | 337 | 32% helix, 23% strand | Q6WZB0 |
Ligands and binding sites
- ARG · Arginine · ligand · chains A
- FE2 · Fe (II) ion · metal · chains A
- SIN · Succinic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 97 | 0.75 | 0.96 | 30 | FE2, SIN, ARG |
| 2 | 150 | 0.55 | 0.81 | 24 | empty |
| 3 | 60 | 0.46 | 0.84 | 23 | empty |
| 4 | 57 | 0.35 | 0.78 | 16 | empty |
| 5 | 67 | 0.31 | 0.75 | 15 | empty |
Compared structures
- 6ALQ · VioC L-arginine hydroxylase bound to Fe(II), L-arginine, and succinate · the same entry in another collection · chain A against A, TM-score 1.00
- Q6WZB0 · AlphaFold monomer V2.0 prediction for alpha-ketoglutarate-dependent L-arginine… · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6WZB0
- Elsewhere: RCSB PDB 6ALQ · PDBe 6ALQ · UniProt Q6WZB0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.