Research workbench
Structural basis of clps-mediated switch in clpa substrate recognition
Analyse Structural basis of clps-mediated switch in clpa substrate recognition in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1LZW
- Type
- protein
- Length
- 237 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein ylja; ATP-dependent clp protease ATP-binding subunit clpa
- UniProt
- P0A8Q6, P0ABH9
- Ligands
- PT
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein ylja | protein | 91 | 47% helix, 22% strand | P0A8Q6 |
| B | ATP-dependent clp protease ATP-binding subunit clpa | protein | 146 | 60% helix, 4% strand | P0ABH9 |
Ligands and binding sites
- PT · Platinum (II) ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 73 | 0.35 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 857 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 1LZW · Structural basis of ClpS-mediated switch in ClpA substrate recognition · the same entry in another collection · chain A against A, TM-score 1.00
- P0ABH9 · AlphaFold monomer V2.0 prediction for ATP-dependent clp protease ATP- binding subunit… · a predicted model of the same protein · chain B against A, TM-score 0.97
- P0A8Q6 · AlphaFold monomer V2.0 prediction for ATP-dependent clp protease adapter protein clps… · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A8Q6
- Every structure of UniProt P0ABH9
- Elsewhere: RCSB PDB 1LZW · PDBe 1LZW · UniProt P0A8Q6 · UniProt P0ABH9
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.