Research workbench
Crystal structure of the smc head domain with an extended coiled coil bound to the C-terminal domain of scpa derived from pyrococcus furiosus
Analyse Crystal structure of the smc head domain with an extended coiled coil bound to… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5XNS
- Type
- protein
- Length
- 468 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromosome partition protein smc; Segregation and condensation protein a
- UniProt
- Q8TZY2, Q8TZY3
- Pockets
- 3 · best druggability 0.58
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chromosome partition protein smc | protein | 398 | 47% helix, 21% strand | Q8TZY2 |
| C | Segregation and condensation protein a | protein | 70 | 54% helix, 17% strand | Q8TZY3 |
Ligands and binding sites
- CIT · Citric acid · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 238 | 0.58 | 0.79 | 33 | empty |
| 2 | 187 | 0.46 | 0.75 | 28 | empty |
| 3 | 54 | 0.30 | 0.76 | 12 | empty |
Interfaces
1 interface between chains.
- A–C · 1312 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 5XNS · Crystal structure of the Smc head domain with an extended coiled coil bound to the… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8TZY2 · AlphaFold monomer V2.0 prediction for chromosome partition protein smc (Q8TZY2) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TZY2
- Every structure of UniProt Q8TZY3
- Elsewhere: RCSB PDB 5XNS · PDBe 5XNS · UniProt Q8TZY2 · UniProt Q8TZY3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.