MolNFT v1 · #430953 · protein
AlphaFold monomer V2.0 prediction for chromosome partition protein smc (Q8TZY2)
Q8TZY2: “AlphaFold monomer V2.0 prediction for chromosome partition protein smc (Q8TZY2)”. 3 pockets (best druggability 0.62). MolNFT v1 #430953 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q8TZY2
- Type
- protein
- Length
- 1,177 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1a69708f6b83eF47B9dedd976F90a17160DB117a
- Molecule
- Chromosome partition protein smc
- UniProt
- Q8TZY2
- Pockets
- 3 · best druggability 0.62
Structure
1 distinct chain · 71% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chromosome partition protein smc | protein | 1177 | 71% helix, 10% strand | Q8TZY2 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 248 | 0.62 | 0.81 | 25 | empty |
| 2 | 163 | 0.47 | 0.76 | 18 | empty |
| 3 | 57 | 0.26 | 0.72 | 13 | empty |
Compared structures
- 5XNS · Crystal structure of the smc head domain with an extended coiled coil bound to the… · an experimental structure of the same protein · chain A against A, TM-score 0.32
- 5XNS · Crystal structure of the Smc head domain with an extended coiled coil bound to the… · an experimental structure of the same protein · chain A against A, TM-score 0.32
- 4I99 · Crystal structure of the SmcHead bound to the C-winged helix domain of ScpA · an experimental structure of the same protein · chain A against B, TM-score 0.27
- 4I99 · Crystal structure of the smchead bound to the C-winged helix domain of scpa · an experimental structure of the same protein · chain A against B, TM-score 0.27
- 4RSJ · Pyrococcus furiosus smc hinge domain with an extended coiled coil · an experimental structure of the same protein · chain A against D, TM-score 0.20
- 4RSJ · Pyrococcus furiosus Smc hinge domain with an extended coiled coil · an experimental structure of the same protein · chain A against D, TM-score 0.20
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TZY2
- Elsewhere: UniProt Q8TZY2 · AlphaFold DB Q8TZY2
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