Research workbench
Crystal structure of SMAD5-MH1/GC-bre DNA complex
Analyse Crystal structure of SMAD5-MH1/GC-bre DNA complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5X6H
- Type
- protein + DNA
- Length
- 129 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mothers against decapentaplegic homolog 5; DNA…
- UniProt
- P97454
- Ligands
- ZN
Structure
x-ray diffraction · 2 distinct chains · 42% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | Mothers against decapentaplegic homolog 5 | protein | 115 | 42% helix, 16% strand | P97454 |
| E | DNA (5'-D(P*GP*TP*AP*TP*GP*GP*CP*GP*CP*CP*AP*TP*AP*C)-3') | dna | 14 | — | — |
Ligands and binding sites
- ZN · Zinc ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- B–E · 373 Ų buried · 8 hydrogen bonds · protein-nucleic
Compared structures
- 5X6H · Crystal Structure of SMAD5-MH1/GC-BRE DNA complex · the same entry in another collection · chain B against B, TM-score 1.00
- P97454 · AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 5 (P97454) · a predicted model of the same protein · chain B against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P97454
- Elsewhere: RCSB PDB 5X6H · PDBe 5X6H · UniProt P97454
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.