UniProt P97454
Mothers against decapentaplegic homolog 5 (P97454)
Mothers against decapentaplegic homolog 5 (UniProt P97454): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P97454
- Protein
- Mothers against decapentaplegic homolog 5
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 3 records with a druggable one
Structures
7 records of P97454 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5X6G | Crystal Structure of SMAD5-MH1/palindromic SBE DNA complex | x-ray diffraction | A, B | ZN | 3 (best 0.65) |
| 5X6G | Crystal structure of SMAD5-MH1/PALINDROMIC sbe DNA complex | x-ray diffraction | A, B | ZN | — |
| 5X6H | Crystal Structure of SMAD5-MH1/GC-BRE DNA complex | x-ray diffraction | B | ZN | — |
| 5X6H | Crystal structure of SMAD5-MH1/GC-bre DNA complex | x-ray diffraction | B | ZN | — |
| 5X6M | Crystal Structure of SMAD5-MH1 in complex with a composite DNA sequence | x-ray diffraction | B, A, E, F | ZN | 12 (best 0.58) |
| 5X6M | Crystal structure of SMAD5-MH1 in complex with a composite DNA sequence | x-ray diffraction | B, A, E, F | ZN | — |
| P97454 | AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 5 (P97454) | predicted | A | — | 5 (best 0.57) |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 5X6H chain B against the predicted model P97454: TM-score 0.97, RMSD 0.81 Å
- 5X6H chain B against the predicted model P97454: TM-score 0.97, RMSD 0.81 Å
- 5X6M chain F against the predicted model P97454: TM-score 0.86, RMSD 1.14 Å
- 5X6M chain E against the predicted model P97454: TM-score 0.86, RMSD 1.15 Å
- 5X6M chain E against the predicted model P97454: TM-score 0.86, RMSD 1.15 Å
- 5X6M chain B against the predicted model P97454: TM-score 0.85, RMSD 1.28 Å
- 5X6M chain B against the predicted model P97454: TM-score 0.85, RMSD 1.28 Å
- 5X6M chain A against the predicted model P97454: TM-score 0.85, RMSD 1.21 Å
- 5X6M chain A against the predicted model P97454: TM-score 0.85, RMSD 1.21 Å
- 5X6G chain A against the predicted model P97454: TM-score 0.85, RMSD 1.50 Å
Elsewhere
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