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Crystal structure of the SKP1-FBXW7-DISC1 complex

Analyse Crystal structure of the SKP1-FBXW7-DISC1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5V4B
Type: protein
Length: 600 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P63208, Q969H0
Ligands: SO4

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	146	—	P63208
B	—	protein	444	—	Q969H0
C	—	protein	10	—	—

Ligands and binding sites

SO4 · Sulfate ion · ion · 9 copies · chains B
IMD · Imidazole · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5V4B · Crystal structure of the Skp1-FBXW7-DISC1 complex · the same entry in another collection · chain A against A, TM-score 1.00
Q969H0 · AlphaFold monomer V2.0 prediction for F-BOX/WD repeat-containing protein 7 (Q969H0) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P63208
Every structure of UniProt Q969H0
Elsewhere: RCSB PDB 5V4B · PDBe 5V4B · UniProt P63208 · UniProt Q969H0

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