UniProt Q969H0
F-box/WD repeat-containing protein 7 (Q969H0)
F-box/WD repeat-containing protein 7 (UniProt Q969H0): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q969H0
- Protein
- F-box/WD repeat-containing protein 7
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
14 records of Q969H0 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OVP | Structure of the Skp1-Fbw7 complex | x-ray diffraction | B | — | — |
| 2OVP | Structure of the SKP1-FBW7 complex | x-ray diffraction | B | — | — |
| 2OVQ | Structure of the Skp1-Fbw7-CyclinEdegC complex | x-ray diffraction | B | — | — |
| 2OVQ | Structure of the SKP1-FBW7-cyclinedegc complex | x-ray diffraction | B | — | — |
| 2OVR | Structure of the Skp1-Fbw7-CyclinEdegN complex | x-ray diffraction | B | — | — |
| 2OVR | Structure of the SKP1-FBW7-cyclinedegn complex | x-ray diffraction | B | — | — |
| 5IBK | Skp1-F-box in complex with a ubiquitin variant | x-ray diffraction | B, E | — | — |
| 5IBK | SKP1-F-box in complex with a ubiquitin variant | x-ray diffraction | B, E | — | — |
| 5V4B | Crystal structure of the Skp1-FBXW7-DISC1 complex | x-ray diffraction | B | SO4 | 3 (best 0.80) |
| 5V4B | Crystal structure of the SKP1-FBXW7-DISC1 complex | x-ray diffraction | B | SO4 | — |
| 7T1Y | Structure of the Fbw7-Skp1-MycCdegron complex | x-ray diffraction | B | SO4 | 3 (best 0.79) |
| 7T1Y | Structure of the FBW7-SKP1-myccdegron complex | x-ray diffraction | B | SO4 | — |
| 7T1Z | Structure of the FBW7-SKP1-mycndegron complex | x-ray diffraction | B | SO4 | — |
| Q969H0 | AlphaFold monomer V2.0 prediction for F-BOX/WD repeat-containing protein 7 (Q969H0) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 5 records
Experiment against prediction
- 7T1Y chain B against the predicted model Q969H0: TM-score 0.97, RMSD 1.15 Å
- 7T1Y chain B against the predicted model Q969H0: TM-score 0.97, RMSD 1.15 Å
- 2OVR chain B against the predicted model Q969H0: TM-score 0.96, RMSD 1.05 Å
- 2OVR chain B against the predicted model Q969H0: TM-score 0.96, RMSD 1.05 Å
- 7T1Z chain B against the predicted model Q969H0: TM-score 0.96, RMSD 1.13 Å
- 2OVQ chain B against the predicted model Q969H0: TM-score 0.96, RMSD 1.06 Å
- 2OVQ chain B against the predicted model Q969H0: TM-score 0.96, RMSD 1.06 Å
- 5V4B chain B against the predicted model Q969H0: TM-score 0.96, RMSD 0.87 Å
- 5V4B chain B against the predicted model Q969H0: TM-score 0.96, RMSD 0.87 Å
- 2OVP chain B against the predicted model Q969H0: TM-score 0.95, RMSD 1.29 Å
Elsewhere
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