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Crystal structure of inosine 5'-monophosphate dehydrogenase from clostridium perfringens complexed with imp and P176

Analyse Crystal structure of inosine 5'-monophosphate dehydrogenase from clostridium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5UWX
Type: protein
Length: 1,377 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: A0A127ELD1
Ligands: 8L7, IMP

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	346	—	A0A127ELD1
B	—	protein	344	—	A0A127ELD1
C	—	protein	346	—	A0A127ELD1
D	—	protein	341	—	A0A127ELD1

Ligands and binding sites

8L7 · N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine · ligand · 4 copies · chains A, B, C, D
IMP · Inosinic acid · ligand · 4 copies · chains A, B, C, D
MPD · (4S)-2-methyl-2,4-pentanediol · additive · 4 copies · chains A, B, C, D
ACY · Acetic acid · additive · 3 copies · chains A, C, D
MRD · (4R)-2-methylpentane-2,4-diol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5UWX · Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens… · the same entry in another collection · chain A against A, TM-score 1.00

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Every structure of UniProt A0A127ELD1
Elsewhere: RCSB PDB 5UWX · PDBe 5UWX · UniProt A0A127ELD1

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