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Ligand · 8L7

8L7 · N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine

8L7, N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine (C24 H30 Cl N3 O5, 476.0 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site…

Component
8L7
Formula
C24 H30 Cl N3 O5
Class
ligand
Structures
3
PDB entries
2

Binding sites

8L7 in 3 structures; the first of them:

  • 5UWX · Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens… · 8L7 A500 · binds VAL224, ALA248, HIS249, SER252, GLY254, VAL255, THR305, MET386 and 9 more
  • 5URQ · Crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from… · 8L7 A502 · binds VAL224, SER245, ALA246, HIS247, SER250, GLY252, THR303, MET384 and 10 more
  • 5UWX · Crystal structure of inosine 5'-monophosphate dehydrogenase from clostridium perfringens… · 8L7 A500 · binds VAL224, ALA248, HIS249, SER252, GLY254, VAL255, THR305, MET386 and 9 more

Residues it binds most

GLY 16, SER 16, VAL 16, MET 16, THR 16, ALA 16, GLU 16, HIS 16, TYR 10, ILE 6 (residue and the binding sites it lines).

Found with

  • IMP · Inosinic acid
  • ACY · Acetic acid
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • MRD · (4R)-2-methylpentane-2,4-diol
  • K · Potassium ion

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