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Ligand · 8L7

8L7 · N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine

8L7, N-{2-chloro-5-[({2-[3-(prop-1-en-2-yl)phenyl]propan-2-yl}carbamoyl)amino]phenyl}-alpha-D-ribofuranosylamine (C24 H30 Cl N3 O5, 476.0 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site…

Component
8L7
Formula
C24 H30 Cl N3 O5
Class
ligand
Structures
4
PDB entries
2

Binding sites

8L7 in 4 structures; the first of them:

  • 5URQ · Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from… · 8L7 A502 · binds VAL224, SER245, ALA246, HIS247, SER250, LYS251, GLY252, ILE253 and 14 more
  • 5UWX · Crystal Structure of Inosine 5'-monophosphate Dehydrogenase from Clostridium perfringens… · 8L7 A500 · binds VAL224, THR247, ALA248, HIS249, SER252, GLY254, VAL255, THR305 and 13 more
  • 5URQ · Crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from… · 8L7 A502 · binds VAL224, SER245, ALA246, HIS247, SER250, LYS251, GLY252, ILE253 and 14 more
  • 5UWX · Crystal structure of inosine 5'-monophosphate dehydrogenase from clostridium perfringens… · 8L7 A500 · binds VAL224, THR247, ALA248, HIS249, SER252, GLY254, VAL255, THR305 and 13 more

Residues it binds most

SER 24, VAL 24, GLY 24, MET 24, PRO 24, THR 24, ALA 24, GLU 24, HIS 24, TYR 18 (residue and the binding sites it lines).

Found with

  • IMP · Inosinic acid
  • K · Potassium ion
  • ACY · Acetic acid
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • MRD · (4R)-2-methylpentane-2,4-diol

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