Research workbench
Prommp-7 with heparin octasaccharide bridging between domains
Analyse Prommp-7 with heparin octasaccharide bridging between domains in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5UE2
- Type
- protein
- Length
- 247 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Matrilysin
- EC
- 3.4.24.23
- UniProt
- P09237
- Ligands
- SGN, IDS, CA, ZN
- Pockets
- 4 · best druggability 0.61
Structure
solution nmr · 1 distinct chain · 33% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Matrilysin (EC 3.4.24.23) | protein | 247 | 33% helix, 9% strand | P09237 |
Ligands and binding sites
- SGN · 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose · sugar · 4 copies · chains A
- IDS · 2-O-sulfo-alpha-L-idopyranuronic acid · sugar · 4 copies · chains A
- CA · Calcium ion · metal · 2 copies · chains A
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 388 | 0.61 | 0.77 | 43 | SGN |
| 2 | 214 | 0.49 | 0.75 | 31 | empty |
| 3 | 52 | 0.37 | 0.80 | 12 | empty |
| 4 | 59 | 0.31 | 0.75 | 11 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09237
- Elsewhere: RCSB PDB 5UE2 · PDBe 5UE2 · UniProt P09237
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.