GL1X · GenesisL1 explorer

UniProt P09237

Matrilysin (P09237)

Matrilysin (UniProt P09237), EC 3.4.24.23: 23 experimental structures on GenesisL1, 6 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P09237
Protein
Matrilysin
EC
3.4.24.23
Experimental structures
23
Predicted models
0
Ligands
6
Pockets
3 · 0 records with a druggable one

Structures

23 records of P09237 in the MolNFT archive: 23 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1MMPMatrilysin complexed with carboxylate inhibitorx-ray diffractionA, B——
1MMPMatrilysin complexed with carboxylate inhibitorx-ray diffractionA, B——
1MMQMatrilysin complexed with hydroxamate inhibitorx-ray diffractionA——
1MMQMatrilysin complexed with hydroxamate inhibitorx-ray diffractionA——
1MMRMatrilysin complexed with sulfodiimine inhibitorx-ray diffractionA——
1MMRMatrilysin complexed with sulfodiimine inhibitorx-ray diffractionA——
2DDYSolution Structure of Matrilysin (MMP-7) Complexed to Constraint Conformational Sulfonamide…solution nmrA——
2DDYSolution structure of matrilysin (mmp-7) complexed to constraint conformational sulfonamide…solution nmrA——
2MZENMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7)solution nmrA——
2MZENMR solution structure of the pro form of human matrilysin (prommp-7)solution nmrA——
2MZHNMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Zwitterionic…solution nmrA——
2MZHNMR solution structure of the pro form of human matrilysin (prommp-7) in complex with zwitterionic…solution nmrA——
2MZINMR Solution Structure of the PRO Form of Human Matrilysin (proMMP-7) in Complex with Anionic…solution nmrA——
2MZINMR solution structure of the pro form of human matrilysin (prommp-7) in complex with anionic…solution nmrA——
2Y6CThe Discovery of MMP7 inhibitors Exploiting a Novel Selectivity Triggerx-ray diffractionA——
2Y6CThe discovery of MMP7 inhibitors exploiting a novel selectivity triggerx-ray diffractionA——
2Y6DThe Discovery of MMP7 Inhibitors Exploiting a Novel Selectivity Triggerx-ray diffractionA——
2Y6DThe discovery of MMP7 inhibitors exploiting a novel selectivity triggerx-ray diffractionA——
5UE2Prommp-7 with heparin octasaccharide bridging between domainssolution nmrASGN, IDS, CA, ZN—
5UE5proMMP-7 with heparin octasaccharide bound to the catalytic domainsolution nmrASGN, IDS, CA, ZN2 (best 0.49)
5UE5Prommp-7 with heparin octasaccharide bound to the catalytic domainsolution nmrASGN, IDS, CA, ZN—
8K4ZCrystal structure of human MMP-7 in complex with inhibitorx-ray diffractionACA, ZN, IOD, CL1 (best 0.49)
P09237AlphaFold monomer V2.0 prediction for matrilysin (P09237)———

Ligands

  • CA · Calcium ion · in 4 records
  • ZN · Zinc ion · in 4 records
  • IDS · 2-O-sulfo-alpha-L-idopyranuronic acid · in 3 records
  • SGN · 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose · in 3 records
  • CL · Chloride ion · in 1 record
  • IOD · Iodide ion · in 1 record

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.