Research workbench

Crystal structure of the GLUA2 ligand-binding domain (S1S2J-L504Y- N775S) in complex with glutamate and BPAM121 at 1.78 a resolution

Analyse Crystal structure of the GLUA2 ligand-binding domain (S1S2J-L504Y- N775S) in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5O9A
Type: protein
Length: 1,054 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P19491
Ligands: 7M6, SO4, CL

Structure

x-ray diffraction · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C	—	protein	264	—	P19491
B	—	protein	265	—	P19491
D	—	protein	261	—	P19491

Ligands and binding sites

7M6 · 7-chloro-4-(2-fluoroethyl)-2,3-dihydro-1,2,4-benzothiadiazine 1,1-dioxide · ligand · 4 copies · chains A, B, C, D
SO4 · Sulfate ion · ion · 16 copies · chains A, B, C, D
CL · Chloride ion · ion · 7 copies · chains A, B, C, D
GOL · Glycerol · additive · 4 copies · chains A, B, C
EDO · 1,2-ethanediol · additive · chains A, B
CIT · Citric acid · additive · chains C
PEG · Di(hydroxyethyl)ether · additive · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5O9A · Crystal structure of the GluA2 ligand-binding domain (S1S2J-L504Y-N775S) in complex with… · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19491
Elsewhere: RCSB PDB 5O9A · PDBe 5O9A · UniProt P19491

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.