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The dimeric structure of ll-37 crystallized in dpc

Analyse The dimeric structure of ll-37 crystallized in dpc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5NNT
Type: protein
Length: 67 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cathelicidin antimicrobial peptide
UniProt: P49913
Ligands: DPV

Structure

x-ray diffraction · 2 distinct chains · 75% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cathelicidin antimicrobial peptide	protein	34	74% helix, 0% strand	P49913
B	Cathelicidin antimicrobial peptide	protein	33	76% helix, 0% strand	P49913

Ligands and binding sites

DPV · dodecyl 2-(trimethylammonio)ethyl phosphate · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 575 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

5NNT · The dimeric structure of LL-37 crystallized in DPC · the same entry in another collection · chain A against A, TM-score 1.00
P49913 · AlphaFold monomer V2.0 prediction for cathelicidin antimicrobial peptide (P49913) · a predicted model of the same protein · chain B against A, TM-score 0.66

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49913
Elsewhere: RCSB PDB 5NNT · PDBe 5NNT · UniProt P49913

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