UniProt P49913
Cathelicidin antimicrobial peptide (P49913)
Cathelicidin antimicrobial peptide (UniProt P49913): 34 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49913
- Protein
- Cathelicidin antimicrobial peptide
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 5 · 2 records with a druggable one
Structures
35 records of P49913 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2FBS | Solution structure of the LL-37 core peptide bound to detergent micelles | solution nmr | N | — | — |
| 2FBS | Solution structure of the ll-37 core peptide bound to detergent micelles | solution nmr | N | — | — |
| 2FBU | Solution structure of the N-terminal fragment of human LL-37 | solution nmr | H | — | — |
| 2FBU | Solution structure of the N-terminal fragment of human ll-37 | solution nmr | H | — | — |
| 2FCG | Solution structure of the C-terminal fragment of human LL-37 | solution nmr | F | — | — |
| 2FCG | Solution structure of the C-terminal fragment of human ll-37 | solution nmr | F | — | — |
| 2K6O | Human LL-37 Structure | solution nmr | A | — | — |
| 2K6O | Human ll-37 structure | solution nmr | A | — | — |
| 2LMF | Solution structure of human LL-23 bound to membrane-mimetic micelles | solution nmr | A | — | — |
| 2LMF | Solution structure of human ll-23 bound to membrane-mimetic micelles | solution nmr | A | — | — |
| 2NA3 | NMR Structure of KR-12: A minimalized domain derived from the human cathelicidin LL-37 | solution nmr | A | — | — |
| 2NA3 | NMR structure of kr-12: a minimalized domain derived from the human cathelicidin ll-37 | solution nmr | A | — | — |
| 4EYC | Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD) | x-ray diffraction | A, B | — | — |
| 4EYC | Crystal structure of the cathelin-like domain of human cathelicidin ll-37 (hcld) | x-ray diffraction | A, B | — | — |
| 5NMN | Atomic resolution structure of LL-37 in a monomeric state | x-ray diffraction | A | NA | — |
| 5NMN | Atomic resolution structure of ll-37 in a monomeric state | x-ray diffraction | A | NA | — |
| 5NNK | The structure of LL-37 crystallized in the presence LDAO | x-ray diffraction | A | — | — |
| 5NNK | The structure of ll-37 crystallized in the presence ldao | x-ray diffraction | A | — | — |
| 5NNM | The crystal structure of dimeric LL-37 | x-ray diffraction | A, B | CO3 | — |
| 5NNM | The crystal structure of dimeric ll-37 | x-ray diffraction | A, B | CO3 | — |
| 5NNT | The dimeric structure of LL-37 crystallized in DPC | x-ray diffraction | A, B | DPV | — |
| 5NNT | The dimeric structure of ll-37 crystallized in dpc | x-ray diffraction | A, B | DPV | — |
| 5XNG | EFK17A structure in microgel MAA60 | solution nmr | A | — | — |
| 5XRX | EFK17DA structure in Microgel MAA60 | solution nmr | A | — | — |
| 5XRX | EFK17DA structure in microgel MAA60 | solution nmr | A | — | — |
| 6S6M | Crystal structure of the human LL37(17-29) antimicrobial peptide | x-ray diffraction | A, B | — | — |
| 6S6M | Crystal structure of the human LL37(17-29) antimicrobial peptide | x-ray diffraction | A, B | — | — |
| 7NPQ | Crystal structure of the human LL37(17-29) I24C mutant antimicrobial peptide | x-ray diffraction | A, B | — | — |
| 7NPQ | Crystal structure of the human LL37(17-29) I24C mutant antimicrobial peptide | x-ray diffraction | A, B | — | — |
| 7PDC | The structure of the human tetrameric LL-37 peptide in a channel conformation | x-ray diffraction | A, B | CL | — |
| 7PDC | The structure of the human tetrameric ll-37 peptide in a channel conformation | x-ray diffraction | A, B | CL | — |
| 7SAY | Fragment of streptococcal M87 protein fused to GCN4 adaptor in complex with human cathelicidin | x-ray diffraction | E, F | — | 2 (best 0.56) |
| 7SAY | Fragment of streptococcal M87 protein fused to GCN4 adaptor in complex with human cathelicidin | x-ray diffraction | E, F | — | — |
| 8DEW | Cryo-electron microscopy structure of Neisseria gonorrhoeae multidrug efflux pump MtrD with LL-37… | electron microscopy | D | — | 3 (best 0.87) |
| P49913 | AlphaFold monomer V2.0 prediction for cathelicidin antimicrobial peptide (P49913) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4EYC chain B against the predicted model P49913: TM-score 0.94, RMSD 1.15 Å
- 4EYC chain B against the predicted model P49913: TM-score 0.94, RMSD 1.15 Å
- 4EYC chain A against the predicted model P49913: TM-score 0.92, RMSD 1.51 Å
- 4EYC chain A against the predicted model P49913: TM-score 0.92, RMSD 1.51 Å
- 6S6M chain A against the predicted model P49913: TM-score 0.82, RMSD 0.26 Å
- 6S6M chain A against the predicted model P49913: TM-score 0.82, RMSD 0.26 Å
- 6S6M chain B against the predicted model P49913: TM-score 0.81, RMSD 0.28 Å
- 6S6M chain B against the predicted model P49913: TM-score 0.81, RMSD 0.28 Å
- 7NPQ chain B against the predicted model P49913: TM-score 0.80, RMSD 0.20 Å
- 7NPQ chain B against the predicted model P49913: TM-score 0.80, RMSD 0.20 Å
Elsewhere
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