Crystal structure of HLA-DRB1*04:01 with the alpha-enolase peptide 326-340

Structure

x-ray diffraction · 3 distinct chains.

Ligands and binding sites

• URE · Urea · ligand · 2 copies · chains A, B
• MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains B, C
• MRD · (4R)-2-methylpentane-2,4-diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 5NI9 · Crystal structure of HLA-DRB1*04:01 with the alpha-enolase peptide 326-340 · the same entry in another collection · chain A against A, TM-score 1.00
• P01903 · AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dr alpha… · a predicted model of the same protein · chain A against A, TM-score 0.96
• P06733 · AlphaFold monomer V2.0 prediction for alpha-enolase (P06733) · a predicted model of the same protein · chain C against A, TM-score 0.30

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P01903
• Every structure of UniProt P13760
• Every structure of UniProt P06733
• Elsewhere: RCSB PDB 5NI9 · PDBe 5NI9 · UniProt P01903 · UniProt P13760 · UniProt P06733