Research workbench
Cocrystal structure of camp-dependent protein kinase (PKA) in complex with the methylated fasudil-derived fragment N-methylisoquinoline-5- sulfonamide (ligand 02)
Analyse Cocrystal structure of camp-dependent protein kinase (PKA) in complex with the… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5M0L
- Type
- protein
- Length
- 358 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P25321, P61925
- Ligands
- 7CT
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 340 | — | P25321 |
| B | — | protein | 18 | — | P61925 |
Ligands and binding sites
- 7CT · ~{N}-methylisoquinoline-5-sulfonamide · ligand · 2 copies · chains A
- MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5M0L · Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with the methylated… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P25321
- Every structure of UniProt P61925
- Elsewhere: RCSB PDB 5M0L · PDBe 5M0L · UniProt P25321 · UniProt P61925
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